ArticleFrontiers in human neuroscience2022
Balance Impairment in Fahr's Disease: Mixed Signs of Parkinsonism and Cerebellar Disorder. A Case Study.
Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06343558 (Gait and Balance Impairment in Rare and Very Rare Neurological Diseases), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Gait and Balance Impairment in Rare and Very Rare Neurological Diseases
Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Challenging Diagnosis of Fahr's Disease Mimicking Parkinson's Disease: A Case Report.Clinical case reports · 2025Article
- Implementation of the sensory organization test with the CAREN system: a pilot study.Frontiers in bioengineering and biotechnology · 2025Article
- Plantar flexors are the main engine of walking in healthy adults.Frontiers in sports and active living · 2025Article
- In Myotonic Dystrophy Type 1 Head Repositioning Errors Suggest Impaired Cervical Proprioception.Journal of clinical medicine · 2024Article
- Fatigue may improve equally after balance and endurance training in multiple sclerosis: a randomised, crossover clinical trial.Frontiers in neurology · 2024Article
- Differential Item Functioning of the Mini-BESTest Balance Measure: A Rasch Analysis Study.International journal of environmental research and public health · 2023Article
- Article
- Incongruity of Geometric and Spectral Markers in the Assessment of Body Sway.Frontiers in neurology · 2022Article
- Balance impairment in myotonic dystrophy type 1: Dynamic posturography suggests the coexistence of a proprioceptive and vestibular deficit.Frontiers in human neuroscience · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fahr's disease is a rare idiopathic degenerative disease characterized by calcifications in the brain, and has also been associated with balance impairment. However, a detailed analysis of balance in these patients has not been performed. A 69-year-old woman with Fahr's disease presented with a long-lasting subjective imbalance. Balance was analyzed using both clinical (EquiScale, Timed Up and Go test, and Dizziness Handicap Inventory-short form) and instrumented tests (the sway of the body center of mass during quiet, perturbed, and self-perturbed stance, and the peak curvature of the center of mass during single stance while walking on a force-treadmill). The patient's balance was normal during clinical tests and walking. However, during standing, a striking impairment in vestibular control of balance emerged. The balance behavior displayed mixed parkinsonian (e.g., slowness and reduced amplitude of movement) and cerebellar (e.g., increased sway during standing in all conditions and decomposition of movement) features, with a discrepancy between the high severity of the static and the low severity of the dynamic balance impairment. The balance impairment characteristics outlined in this study could help neurologists and physiatrists detect, stage, and treat this rare condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.