Evidence map›Paper›PMID 35355242›Full record

ArticleAging clinical and experimental research2022

COVID-19 as an effect modifier of the relationship between age and in-hospital survival in older patients admitted to an Italian Emergency Department.

Alberto Zucchelli, Catello Sepe, Luca Tarozzi, Anna Garelli, Francesca Benedusi, Samuele Pignataro, Ciro Paolillo, Alessandra Marengoni

Abstract read
In one paragraph

Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alberto ZucchelliDepartment of Clinical and Experimental Sciences, Università degli Studi di Brescia, viale Europa 11, 25123, Brescia, Italy. a.zucchelli001@unibs.it.ORCID http://orcid.org/0000-0001-5992-8506
Catello SepeEmergency Department Unit, ASST Spedali Civili, Brescia, Italy.
Luca TarozziEmergency Department Unit, ASST Spedali Civili, Brescia, Italy.
Anna GarelliEmergency Department Unit, ASST Spedali Civili, Brescia, Italy.
Francesca BenedusiEmergency Department Unit, ASST Spedali Civili, Brescia, Italy.
Samuele PignataroEmergency Department Unit, ASST Spedali Civili, Brescia, Italy.
Ciro Paolillo *Emergency Department Unit, ASST Spedali Civili, Brescia, Italy.
Alessandra Marengoni *Department of Clinical and Experimental Sciences, Università degli Studi di Brescia, viale Europa 11, 25123, Brescia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe SARS-CoV-2 pandemic modified how persons got into contact with emergency services, particularly during the first wave.

aimThe aim is to describe the characteristics of older persons with and without COVID-19 visiting the Emergency Department of a tertiary hospital and to investigate the impact of age on in-hospital survival in the two groups.

methodsPatients older than 70 years were followed-up till discharge or in-hospital death. Cox regression models stratified by COVID-19 diagnosis were used to investigate survival.

resultsOut of 896 patients, 36.7% had COVID-19. Those without COVID-19 were older and affected by a higher number of chronic conditions but exhibited lower mortality (10.5 vs 48.1%). After the adjustment, age was associated with mortality only among those with COVID-19. DISCUSSION: COVID-19 modified the relationship between older age and in-hospital survival: whether this finding is explained by other biological vulnerabilities or by a selection of treatments based on age should be further investigated.

Indexed as

COVID-19AgedAged, 80 and overCOVID-19 TestingEmergency Service, HospitalHospital MortalityHumansRetrospective StudiesSARS-CoV-2Tertiary Care CentersCOVID-19 survivalEmergency DepartmentOlder age

Identifiers

PMID35355242
PMCPMC8966861

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.