Evidence map›Paper›PMID 35354967›Full record

ReviewNature reviews. Cardiology2022

Sirtuins in atherosclerosis: guardians of healthspan and therapeutic targets.

Mandy O J Grootaert, Martin R Bennett

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 78 citations in OpenAlex.

  1. Trial
  2. Review
  3. HMGB1 as a danger signal in vascular remodeling.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. ATF3 Deficiency Exacerbates Ageing-Induced Atherosclerosis and Clinical Intervention Strategy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  11. Single-Cell Multimodal Profiling Reveals a Novel CD26Arteriosclerosis, thrombosis, and vascular biology · 2025
    Article
  12. Article
  13. Roles of SIRT3 in aging and aging-related diseases.International journal of biological sciences · 2025
    Review
  14. Review
  15. Observational
  16. Review
  17. Article
  18. Review
  19. Review
  20. LARP7 overexpression alleviates aortic senescence and atherosclerosis.Journal of cellular and molecular medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Mandy O J GrootaertDivision of Cardiovascular Medicine, University of Cambridge, Addenbrookes Hospital, Cambridge, UK. mandy.grootaert@kuleuven.be.
Martin R BennettDivision of Cardiovascular Medicine, University of Cambridge, Addenbrookes Hospital, Cambridge, UK. mrb24@medschl.cam.ac.uk.ORCID http://orcid.org/0000-0002-2565-1825
University of Cambridge · GB

Funding

British Heart Foundation CH/2000003/12800British Heart Foundation PG/16/11/32021British Heart Foundation PG/16/24/32090British Heart Foundation PG/16/63/32307British Heart Foundation RG/13/14/30314British Heart Foundation RG/20/2/34763
6 · The paper itself

Abstract

Sirtuins are NAD

Indexed as

AtherosclerosisSirtuinsAnimalsCellular SenescenceHumansMammalsMitochondriaNADNADSirtuins

Identifiers

PMID35354967
OpenAlexW4220784388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.