Evidence map›Paper›PMID 35354863›Full record

ArticleScientific reports2022

Sea anemone Bartholomea annulata venom inhibits voltage-gated Na

Antònia Colom-Casasnovas, Edith Garay, Abraham Cisneros-Mejorado, Manuel B Aguilar, Fernando Lazcano-Pérez, Rogelio O Arellano, Judith Sánchez-Rodríguez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Effect of Crude Extract from the Sea AnemonePharmaceuticals (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Antònia Colom-CasasnovasPosgrado en Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Circuito Exterior S/N, Ciudad Universitaria, C.P. 04510, Coyoacán, Mexico, Mexico.
Edith GarayDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Boulevard Juriquilla 3001, 76230, Juriquilla, Querétaro, C.P, Mexico.
Abraham Cisneros-MejoradoDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Boulevard Juriquilla 3001, 76230, Juriquilla, Querétaro, C.P, Mexico.
Manuel B AguilarDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Boulevard Juriquilla 3001, 76230, Juriquilla, Querétaro, C.P, Mexico.
Fernando Lazcano-PérezUnidad Académica de Sistemas Arrecifales Puerto Morelos, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Prolongación Niños Héroes s/n, Domicilio Conocido, C.P. 77580, Puerto Morelos, Quintana Roo, Mexico.
Rogelio O ArellanoDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Boulevard Juriquilla 3001, 76230, Juriquilla, Querétaro, C.P, Mexico. arellano.ostoa@comunidad.unam.mx.
Judith Sánchez-RodríguezUnidad Académica de Sistemas Arrecifales Puerto Morelos, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Prolongación Niños Héroes s/n, Domicilio Conocido, C.P. 77580, Puerto Morelos, Quintana Roo, Mexico. judithsa@cmarl.unam.mx.
Universidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxin production in nematocysts by Cnidaria phylum represents an important source of bioactive compounds. Using electrophysiology and, heterologous expression of mammalian ion channels in the Xenopus oocyte membrane, we identified two main effects produced by the sea anemone Bartholomea annulata venom. Nematocysts isolation and controlled discharge of their content, revealed that venom had potent effects on both voltage-dependent Na

Indexed as

Cnidarian VenomsSea AnemonesAnimalsgamma-Aminobutyric AcidMammalsReceptors, GABA-ACnidarian Venomsgamma-Aminobutyric AcidReceptors, GABA-A

Identifiers

PMID35354863
PMCPMC8967859
OpenAlexW4221116268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.