Evidence map›Paper›PMID 35354764›Full record

ArticleJournal of microbiology and biotechnology2022

Anticancer Activity of Extremely Effective Recombinant L-Asparaginase from

Doaa B Darwesh, Yahya S Al-Awthan, Imadeldin Elfaki, Salem A Habib, Tarig M Alnour, Ahmed B Darwish, Magdy M Youssef

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Pantoea piersonii IIIF1SW-P2Scientific reports · 2025
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Doaa B DarweshDepartment of Biology, Faculty of Science, Tabuk University, Tabuk 71491, Saudi Arabia.
Yahya S Al-AwthanDepartment of Biology, Faculty of Science, Tabuk University, Tabuk 71491, Saudi Arabia.
Imadeldin ElfakiBiochemistry Department, Faculty of Science, Tabuk University, Tabuk 71491, Saudi Arabia.
Salem A HabibBiochemistry Department, Faculty of Science, Tabuk University, Tabuk 71491, Saudi Arabia.
Tarig M AlnourMedical Laboratory Technology Department, Faculty of Applied Medical Sciences, Tabuk University, Tabuk 71491, Saudi Arabia.
Ahmed B DarwishZoology Department, Faculty of Science, Suez University, El Salam-1, Suez 43533, Egypt.
Magdy M YoussefBiochemistry Division, Chemistry Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.
University of Tabuk · SAMansoura University · EGIbb University · YESuez University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-asparaginase (E.C. 3.5.1.1) purified from bacterial cells is widely used in the food industry, as well as in the treatment of childhood acute lymphoblastic leukemia. In the present study, the

Indexed as

AsparaginaseBurkholderia pseudomalleiEnzyme StabilityEscherichia coliHumansRecombinant ProteinsSubstrate SpecificityAsparaginaseRecombinant ProteinscharacterizationcloningDNAL-asparaginaseleukemiapurification

Identifiers

PMID35354764
PMCPMC9628870
OpenAlexW4220976002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.