Evidence map›Paper›PMID 35354698›Full record

ArticleThe Journal of veterinary medical science2022

Gonadotropin-releasing hormone stimulation of annexin A5 expression in the thymus of male rats.

Mitsumori Kawaminami, Ryota Terashima, Takuya Murata, Shuichi Chiba, Shiro Kurusu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mitsumori KawaminamiLaboratory of Veterinary Physiology, School of Veterinary Medicine, Kitasato University, Aomori, Japan.
Ryota TerashimaLaboratory of Veterinary Physiology, School of Veterinary Medicine, Kitasato University, Aomori, Japan.
Takuya MurataLaboratory of Veterinary Physiology, School of Veterinary Medicine, Okayama University of Science, Ehime, Japan.
Shuichi ChibaLaboratory of Veterinary Physiology, School of Veterinary Medicine, Okayama University of Science, Ehime, Japan.
Shiro KurusuLaboratory of Veterinary Physiology, School of Veterinary Medicine, Kitasato University, Aomori, Japan.
Kitasato University · JPOkayama University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As gonadotropin-releasing hormone (GnRH) is expressed in the thymus, its direct action on thymic cells, including thymic involution, has been suggested. Annexin A5 (ANXA5), a biomarker of GnRH, was used to determine whether GnRH affects the thymus of male rats. Immunohistochemistry showed positive reactions for ANXA5 in large medullary epithelial cells at 30 days of age, and the expression continued until 180 days of age. Organ culture of thymus pieces was performed to examine the direct action of a GnRH agonist (GnRHa) on the expression of Anxa5 and Gnrh mRNA. Thymus tissues obtained from male rats (40-60 days old) were cut into small pieces (2-3 mm

Indexed as

Gonadotropin-Releasing HormoneAnimalsAnnexin A5MaleRatsRNA, MessengerAnnexin A5Gonadotropin-Releasing HormoneRNA, Messengerannexin A5 (ANXA5)gonadotropin-releasing hormone (GnRH)thymus

Identifiers

PMID35354698
PMCPMC9177390
OpenAlexW4220743592

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.