Trial reportPsychiatric services (Washington, D.C.)2022
Socioeconomic Predictors of Treatment Outcomes Among Adults With Major Depressive Disorder.
Trial report in Psychiatric services (Washington, D.C.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Individual Socioeconomic Measures and Change in HoNOS Scores among Persons Attending Adult Community Mental Health Services.Community mental health journal · 2026Article
- Development of a baseline battery to optimize depression treatment assignment in primary care: Balancing breadth and brevity.Journal of affective disorders · 2026Article
- ADHD symptoms and financial debt among adults.BMC psychiatry · 2026Article
- Socioeconomic Status Is Associated With Reward Processing, Interleukin 1β, Striatal Connectivity, and Antidepressant Outcomes in Individuals With Major Depressive Disorder: A CAN-BIND-1 Report.Biological psychiatry global open science · 2026Article
- Parsing Socioeconomic Effects on Treatment Trajectory and Reward Processing in Depression.Biological psychiatry global open science · 2026Article
- Patient and course of care factors impacting time to response and remission in psychotherapy for depression.Frontiers in psychology · 2026Article
- Association of Area Deprivation Index with perinatal and COVID-19 outcomes during the early pandemic: a secondary analysis of a prospective cohort study.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2025Article
- Long-term occupational outcomes in major depressive disorder: a 10-year follow-up study of symptom and comorbidity predictors.BMC psychiatry · 2025Article
- Effectiveness of the Intervention from a Mental Health Day Hospital with Patients with Various Mental Disorders in Burgos, Spain.Journal of clinical medicine · 2025Article
- A systematic review of income and education reporting in psychedelic clinical trials.Nature. Mental health · 2025Article
- Sociodemographic, clinical, and genetic factors associated with self-reported antidepressant response outcomes in the UK Biobank.Psychological medicine · 2025Article
- Intravenous ketamine versus esketamine for depression: a systematic review and meta-analysis.Therapeutic advances in psychopharmacology · 2025Article
- Relationship between social determinants of health and hospitalizations and costs in patients with major depressive disorder.Journal of managed care & specialty pharmacy · 2024Observational
- An Umbrella Review of the Links Between Adverse Childhood Experiences and Substance Misuse: What, Why, and Where Do We Go from Here?Substance abuse and rehabilitation · 2022Review
- Influence of Sociodemographic, Socioeconomic, and Health Factors on Depression in the Peruvian Population: A Cross-Sectional Study.Journal of primary care & community healthArticle
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Authors and funding
7 authors.
Funding
Abstract
objectiveIn this study, the authors sought to examine the impact of socioeconomic variables on outcomes of pharmacotherapy treatments for major depressive disorder in analyses that controlled for treatment access and level of care.
methodsThe authors used data from the Combining Medications to Enhance Depression Outcomes study, a prospective clinical trial conducted from March 2008 to April 2014 with 665 adults who had major depressive disorder and were randomly assigned to three pharmacotherapeutic treatments, to develop Bayesian hierarchical models of treatment trajectories for change in Quick Inventory of Depressive Symptomatology-Self-Report ratings. Posterior tail probabilities were used to evaluate the effects of education, income, race-ethnicity, and employment on treatment outcomes.
resultsAfter sex, age, and treatment type were controlled for in the analyses, not having a college education (<16 years of schooling), being unemployed, or being non-White were each associated with slower and less improvement. At the end of treatment (week 12), not having a college degree reduced treatment responses by 9.6% (p=0.045), being unemployed by 6.6% (p=0.007), and being non-White by 11.3% (p<0.001). Treatment response was significantly related to income; having an income at the 25th percentile of the income distribution decreased improvement by 4.8% compared with having an income at the 75th percentile (p=0.018).
conclusionsWithin a short-term, randomized controlled trial, socioeconomic factors had a critical role in the acute response of patients to pharmacotherapy for major depression.
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