Evidence map›Paper›PMID 35354307›Full record

ArticleJDR clinical and translational research2023

Oral Diseases and Oral Health-Related Quality of Life among Kenyan Children and Adolescents with HIV.

Y Wang, F Ramos-Gomez, A M Kemoli, G John-Stewart, D Wamalwa, S Benki-Nugent, J Slyker, A L Seminario

Open access · bronzeAbstract read
In one paragraph

Article in JDR clinical and translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Social Justice in Dental Research.JDR clinical and translational research · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Y WangDivision of Infectious Diseases, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-4822-6514
F Ramos-GomezDivision of Preventative and Restorative Sciences, School of Dentistry, University of California Los Angeles, Los Angeles, CA, USA.
A M KemoliDepartment of Paediatric Dentistry and Orthodontics, University of Nairobi, Nairobi, Kenya.
G John-StewartDepartments of Global Health, Medicine, and Pediatrics, University of Washington, Seattle, WA, USA.
D WamalwaDepartment of Pediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
S Benki-NugentDepartment of Global Health, University of Washington, Seattle, WA, USA.
J SlykerDepartments of Epidemiology and Global Health, University of Washington, Seattle, WA, USA.
A L SeminarioUW Timothy A. DeRouen Center for Global Oral Health, School of Dentistry, University of Washington, Seattle, WA, USA.
University of Washington · USUniversity of California, Los Angeles · USUniversity of Nairobi · KEUniversidad Peruana Cayetano Heredia · PE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
Postdoctoral Training in Global AIDS Prevention ResearchT32MH080634 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Pamina Mae Gorbach · 2007 to 2026
$6.4M
NIAID NIH HHS P30 AI027757NIMH NIH HHS T32 MH080634
6 · The paper itself

Abstract

introductionChildren and adolescents living with HIV (CALHIV) have a higher risk of hard and soft oral tissue diseases as compared with their healthy peers. It is important to increase awareness regarding the need to integrate oral health within medical care among pediatric HIV populations. Studies on associations of oral diseases with oral health-related quality of life (OHRQoL) in CALHIV are lacking. This study examined the association between oral diseases and OHRQoL in Kenyan CALHIV.

methodsThis cross-sectional analysis was nested in a longitudinal cohort study of CALHIV in Nairobi. CALHIV received oral examinations, and the World Health Organization's Oral Health Surveys and Record Form was administered. OHRQoL was measured with the Parental-Caregiver Perceptions Questionnaire, with the subdomains of global, oral symptoms, function limitations, and emotional and social well-being, with higher scores indicating poorer OHRQoL. Linear regression was used to model associations between OHRQoL and oral diseases, adjusting for age at the time of oral examination, CD4 counts, and caregiver's education.

resultsAmong 71 CALHIV, the mean age was 12.6 y (SD, 2.9; range, 10 to <21), and the mean composite OHRQoL score was 12.6 (SD, 11.2). Ulcers (not herpes simplex virus or aphthous) were associated with the worst overall OHRQoL (mean, 21.8; SD, 11.1;

conclusionsOral ulcers, dry mouth, and untreated caries were associated with poorer OHRQoL in CALHIV. Integrating oral health into the primary care of CALHIV may improve their OHRQoL. KNOWLEDGE TRANSFER STATEMENT: This study aimed to determine the association of oral diseases with the oral health-related quality of life of children and adolescents living with HIV (CALHIV). The findings will form part of the evidence to incorporate oral health protocols into care programs for CALHIV. Oral health monitoring has the potential to increase the surveillance of HIV clinical status, monitor the effectiveness of antiretroviral therapy, and improve the oral health-related quality of life of CALHIV.

Indexed as

Dental CariesMouth DiseasesXerostomiaAdolescentChildCross-Sectional StudiesHIV InfectionsHumansKenyaLongitudinal StudiesQuality of LifeUlcerYoung Adultadolescentschildrendental cariesHIV infectionsquality of lifesurveys and questionnaires

Identifiers

PMID35354307
PMCPMC10026160
OpenAlexW4221014683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.