ReviewJournal of child psychology and psychiatry, and allied disciplines2022
Research Review: A guide to computing and implementing polygenic scores in developmental research.
Review in Journal of child psychology and psychiatry, and allied disciplines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed.
- Investigating Relationships Between Genetic Risk, Childhood Maltreatment, and Eating Disorders in Women.Biological psychiatry global open science · 2026Article
- Polygenic profiles in youth with early-onset psychosis and offspring of schizophrenia or bipolar disorder patients.European child & adolescent psychiatry · 2026Article
- Social Isolation, Genetic Susceptibility, Systemic Inflammation and Risk of Abdominal Aortic Aneurysm: A UK Biobank Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- A decade of discovery: Leveraging genomic data in the ABCD study to illuminate adolescent neurodevelopment.Developmental cognitive neuroscience · 2026Review
- Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders.JCPP advances · 2026Article
- Accelerometer-derived rest-activity rhythms, genetic risk, and chronic inflammatory markers and the risk of abdominal aortic aneurysm.Frontiers in public health · 2026Article
- Intergenerational transmission of polygenic predisposition for neuropsychiatric traits on emotional and behavioural difficulties in childhood.Nature communications · 2025Article
- Association analysis between polygenic risk scores and traits: practical guidelines and tutorial with an illustrative data set of schizophrenia.Frontiers in psychiatry · 2025Article
- Growing Up Together in Society (GUTS): A team science effort to predict societal trajectories in adolescence and young adulthood.Developmental cognitive neuroscience · 2024Article
- Polygenic risk for epigenetic aging and adverse life experiences interact to predict growth in adolescent depression in a racially/ethnically diverse sample.Frontiers in psychiatry · 2024Article
- Individual Trajectories of Depressive Symptoms Within Racially-Ethnically Diverse Youth: Associations with Polygenic Risk for Depression and Substance Use Intent and Perceived Harm.Behavior genetics · 2024Article
- Epigenetics applied to child and adolescent mental health: Progress, challenges and opportunities.JCPP advances · 2023Article
- The next 10 years of behavioural genomic research.JCPP advances · 2022Article
- Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes.Journal of child psychology and psychiatry, and allied disciplines · 2022Review
- Commentary: Will genomics revolutionise research on gene-environment interplay?Journal of child psychology and psychiatry, and allied disciplines · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The increasing availability of genotype data in longitudinal population- and family-based samples provides opportunities for using polygenic scores (PGS) to study developmental questions in child and adolescent psychology and psychiatry. Here, we aim to provide a comprehensive overview of how PGS can be generated and implemented in developmental psycho(patho)logy, with a focus on longitudinal designs. As such, the paper is organized into three parts: First, we provide a formal definition of polygenic scores and related concepts, focusing on assumptions and limitations. Second, we give a general overview of the methods used to compute polygenic scores, ranging from the classic approach to more advanced methods. We include recommendations and reference resources available to researchers aiming to conduct PGS analyses. Finally, we focus on the practical applications of PGS in the analysis of longitudinal data. We describe how PGS have been used to research developmental outcomes, and how they can be applied to longitudinal data to address developmental questions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.