ArticlePLoS computational biology2022
Inferring age-specific differences in susceptibility to and infectiousness upon SARS-CoV-2 infection based on Belgian social contact data.
Article in PLoS computational biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Counterfactual evaluation of elementary and secondary school policies in the COVID-19 pandemic.Nature communications · 2026Article
- Differential impacts of the COVID-19 pandemic on sociodemographic groups: A mathematical model framework.PloS one · 2026Article
- Assessing the role of children in the COVID-19 pandemic in Belgium using perturbation analysis.Nature communications · 2025Article
- Identifying the main drivers of transmission in the early phase of the COVID-19 pandemic in Portugal.Scientific reports · 2024Article
- Polymorphisms in the ACE I/D (Tropical medicine and infectious disease · 2024Article
- Social contact patterns following the COVID-19 pandemic: a snapshot of post-pandemic behaviour from the CoMix study.Epidemics · 2024Article
- Detecting and quantifying heterogeneity in susceptibility using contact tracing data.PLoS computational biology · 2024Article
- The impact of quality-adjusted life years on evaluating COVID-19 mitigation strategies: lessons from age-specific vaccination roll-out and variants of concern in Belgium (2020-2022).BMC public health · 2024Article
- Wording the trajectory of the three-year COVID-19 epidemic in a general population - Belgium.BMC public health · 2024Article
- Population age and household structures shape transmission dynamics of emerging infectious diseases: a longitudinal microsimulation approach.Journal of the Royal Society, Interface · 2023Article
- Exploring the impact of population ageing on the spread of emerging respiratory infections and the associated burden of mortality.BMC infectious diseases · 2023Article
- Evaluating the use of social contact data to produce age-specific short-term forecasts of SARS-CoV-2 incidence in England.PLoS computational biology · 2023Article
- Longitudinal social contact data analysis: insights from 2 years of data collection in Belgium during the COVID-19 pandemic.BMC public health · 2023Article
- Evolutionary implications of SARS-CoV-2 vaccination for the future design of vaccination strategies.Communications medicine · 2023Review
- Impact of tiered measures on social contact and mixing patterns of in Italy during the second wave of COVID-19.BMC public health · 2023Article
- Age-specific transmission dynamics under suppression control measures during SARS-CoV-2 Omicron BA.2 epidemic.BMC public health · 2023Article
- Dynamics of non-household contacts during the COVID-19 pandemic in 2020 and 2021 in the Netherlands.Scientific reports · 2023Article
- Association between the Seroprevalence of Antibodies against Seasonal Alphacoronaviruses and SARS-CoV-2 Humoral Immune Response, COVID-19 Severity, and Influenza Vaccination.Journal of clinical medicine · 2023Article
- Policies on children and schools during the SARS-CoV-2 pandemic in Western Europe.Frontiers in public health · 2023Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several important aspects related to SARS-CoV-2 transmission are not well known due to a lack of appropriate data. However, mathematical and computational tools can be used to extract part of this information from the available data, like some hidden age-related characteristics. In this paper, we present a method to investigate age-specific differences in transmission parameters related to susceptibility to and infectiousness upon contracting SARS-CoV-2 infection. More specifically, we use panel-based social contact data from diary-based surveys conducted in Belgium combined with the next generation principle to infer the relative incidence and we compare this to real-life incidence data. Comparing these two allows for the estimation of age-specific transmission parameters. Our analysis implies the susceptibility in children to be around half of the susceptibility in adults, and even lower for very young children (preschooler). However, the probability of adults and the elderly to contract the infection is decreasing throughout the vaccination campaign, thereby modifying the picture over time.
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