Evidence map›Paper›PMID 35353447›Full record

ArticleTransboundary and emerging diseases2022

Investigation into an outbreak of Border disease virus in pigs in England.

Akbar Dastjerdi, Rebecca Strong, S Anna La Rocca, Mark Wessels, Julie Wessels, Kate Whitaker, Ben Strugnell, Susanna Williamson

Open access · bronzeAbstract readNews
In one paragraph

Article in Transboundary and emerging diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Akbar DastjerdiVirology Department, Animal and Plant Health Agency (APHA)-Weybridge, Addlestone, Surrey, UK.ORCID https://orcid.org/0000-0001-6251-6588
Rebecca StrongVirology Department, Animal and Plant Health Agency (APHA)-Weybridge, Addlestone, Surrey, UK.
S Anna La RoccaVirology Department, Animal and Plant Health Agency (APHA)-Weybridge, Addlestone, Surrey, UK.
Mark WesselsAPHA-Preston, Animal Health Centre, Barton, Preston, UK.
Julie WesselsAPHA-Bury St. Edmunds, Suffolk, UK.
Kate WhitakerAPHA-Preston, Animal Health Centre, Barton, Preston, UK.
Ben StrugnellAPHA-Thirsk, West House, Thirsk, UK.
Susanna WilliamsonAPHA-Preston, Animal Health Centre, Barton, Preston, UK.
Animal and Plant Health Agency · GBPreston's College · GBUniversity of the Third Age · GBWest Suffolk Hospital · GB

Funding

Department of Environment, Food and Rural Affairs
6 · The paper itself

Abstract

Border disease (BD) was first reported in 1959 in lambs from the border region of England and Wales. The causative virus (BD virus; BDV) has since been identified in several other ruminant species and pigs. The virus is prevalent in sheep flocks of UK, Europe and USA and has potential to inflict substantial economic losses. Natural BDV infection of pigs was first reported in the UK in 1992 from pigs with haemorrhagic lesions and more recently from healthy pigs in Spain and Japan. Here, a persistent problem of poor growth and anaemia in a small proportion of growing pigs on a mixed pig and sheep holding was investigated and tissues were tested in a pan viral microarray. The microarray detected BDV RNA in several tissues which was further confirmed by sequencing, specific BDV PCR and immunohistochemistry. Phylogenetically, the virus clustered with other BDVs in the sub-genotype 1b. This investigation highlights likely interspecies transmission of pestiviruses and their impact on pestivirus detection and eradication programs.

Indexed as

Border DiseaseBorder disease virusPestivirusSheep DiseasesSwine DiseasesAnimalsDisease OutbreaksGenotypeSheepSwineBorder disease viruscongenital infectionmicroarraypestiviruspigs

Identifiers

PMID35353447
PMCPMC9544453
OpenAlexW4221091804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.