Evidence map›Paper›PMID 35353421›Full record

ArticleJournal of adolescence2022

The mediating role of anxiety/depression symptoms between adverse childhood experiences (ACEs) and somatic symptoms in adolescents.

Rachel Y Lee, Monica L Oxford, Jennifer Sonney, Daniel A Enquobahrie, Kenrick D Cato

Open access · greenAbstract read
In one paragraph

Article in Journal of adolescence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Joint Effects of Adverse Childhood Experiences and Genetic Burden of Depression on Multiple Depressive Symptoms.Stress and health : journal of the International Society for the Investigation of Stress · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rachel Y LeeSchool of Nursing, Columbia University, New York City, New York, USA.ORCID 0000-0002-0392-5848
Monica L OxfordDepartment of Child, Family, and Population Health Nursing, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-0506-843X
Jennifer SonneyDepartment of Child, Family, and Population Health Nursing, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-0766-2918
Daniel A EnquobahrieDepartment of Epidemiology, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-9844-0597
Kenrick D CatoSchool of Nursing, Columbia University, New York City, New York, USA.ORCID 0000-0002-0704-3826
University of Washington · USCity University of New York · US

Funding

Reducing Health Disparities Through Informatics - Genomics SupplementT32NR007969 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SUZANNE BAKKEN, Rebecca Schnall · 2002 to 2026
$7.9M
Reaching Communities through the Design of Information Visualizations (ReDIVis) Toolbox to Address COVID-19 Vaccine Hesitancy and Uptake.P30NR016587 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BAKKEN, SUZANNE, SMALDONE, ARLENE M · 2016 to 2022
$4.3M
NINR NIH HHS P30 NR016587NINR NIH HHS T32 NR007969
6 · The paper itself

Abstract

introductionThis study examines the relationships among recent adverse childhood experiences (ACEs), somatic symptoms, and anxiety/depression symptoms during adolescence and whether anxiety/depression symptoms mediate the relationship between ACEs and somatic symptoms.

methodsLongitudinal prospective data from the Longitudinal Studies of Child Abuse and Neglect study of 1354 children and their primary caregivers in the United States was used in this study. A longitudinal cross-lagged path analysis among recent ACEs, anxiety/depression symptoms, and somatic symptoms at three points during adolescence (ages 12, 14, and 16 years) was conducted.

resultsThe sample was 51% female and 53% African American. The results indicated significant concurrent associations between recent ACEs and increased anxiety/depression symptoms at ages 12, 14, and 16 (β = .27, p < .001; β = .15, p < .001; β = .07, p < .05) and between anxiety/depression symptoms and increased somatic symptoms at ages 12, 14, and 16 years (β = .44, p < .001; β = .39, p < .001; β = .49, p < .001). Moreover, anxiety/depression symptoms significantly mediated the relationship between recent ACEs and concurrent somatic symptoms at ages 12, 14, and 16 years (β = .12, p < .001; β = .06, p < .001; β = .04, p < .05). However, there was no significant relationship between recent ACEs and somatic symptoms.

conclusionThe findings suggest that anxiety/depression symptoms mediate the concurrent relationships between recent ACEs and somatic symptoms at ages 12, 14, and 16. Clinicians should consider assessing anxiety/depression symptoms and possible concurrent exposure to ACEs when caring for adolescents who present with somatic symptoms.

Indexed as

Adverse Childhood ExperiencesMedically Unexplained SymptomsAdolescentAnxietyChildDepressionFemaleHumansMaleProspective StudiesUnited Statesadolescenceadverse childhood experiencesanxietychildhood adversitydepressionsomatic symptoms

Identifiers

PMID35353421
PMCPMC9511877
OpenAlexW4214854880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.