Evidence map›Paper›PMID 35352966›Full record

ArticleAIDS research and human retroviruses2022

Short Communication:Outcomes of Dual Versus Triple Antiretroviral Drug Regimens Among Virally Suppressed Adults in the DC Cohort.

Wei Li Adeline Koay, Jiayang Xiao, Marinella Temprosa, Lindsey P Happ, Anne K Monroe, Amanda D Castel, Natella Y Rakhmanina, DC Cohort Executive Committee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS research and human retroviruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei Li Adeline KoayDivision of Infectious Diseases, Children's National Hospital, Washington, District of Columbia, USA.ORCID 0000-0002-8825-7067
Jiayang XiaoDepartment of Biostatistics and Bioinformatics and Milken Institute School of Public Health, The George Washington University, Washington, District of Columbia, USA.
Marinella TemprosaDepartment of Biostatistics and Bioinformatics and Milken Institute School of Public Health, The George Washington University, Washington, District of Columbia, USA.
Lindsey P HappDepartment of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, District of Columbia, USA.
Anne K MonroeDepartment of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, District of Columbia, USA.ORCID 0000-0003-3201-3845
Amanda D CastelDepartment of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, District of Columbia, USA.
Natella Y RakhmaninaDivision of Infectious Diseases, Children's National Hospital, Washington, District of Columbia, USA.
DC Cohort Executive Committee

Funding

Terry Beirn CPCRA Clinical Trials UnitUM1AI069503 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI KAN, VIRGINIA · 2012 to 2020
$38.5M
The DC Cohort: A Longitudinal Population-Based Cohort Study of People Living with HIV in Washington, DCR24AI152598 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Amanda Derryck Castel, Marinella Temprosa · 2020 to 2026
$37.9M
NIAID NIH HHS R24 AI152598NIAID NIH HHS UM1 AI069503
6 · The paper itself

Abstract

This study explored virological outcomes of two-drug (2DRs) and three-drug (3DRs) antiretroviral regimens in adults with HIV in the DC Cohort. We analyzed 310 treatment-experienced adults with sustained HIV RNA ≤50 copies/mL at baseline, 53 of whom switched to 2DRs and 257 continued 3DRs. Adults on 2DRs and 3DRs had similar demographics (median age 53.3 years, 76.8% cisgender male, 76.1% Black). Adults on 2DRs had more participants with ≥2 comorbidities (62.3% vs. 42.8%,

Indexed as

Anti-HIV AgentsHIV InfectionsAdultAnti-Retroviral AgentsCohort StudiesHumansMaleMiddle AgedRNAViral LoadAnti-HIV AgentsAnti-Retroviral AgentsRNAantiretroviral therapydual therapyHIVregimen simplificationtwo-drug regimen

Identifiers

PMID35352966
PMCPMC9225828

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.