Evidence map›Paper›PMID 35352884›Full record

ArticleYonsei medical journal2022

Impact of Statin Treatment Intensity after Endovascular Revascularization on Lower Extremity Peripheral Artery Disease.

Gwang Sil Kim, Jongkwon Seo, Byung Gyu Kim, Moo-Nyun Jin, Hye Young Lee, Byung Ok Kim, Young Sup Byun

Abstract read
In one paragraph

Article in Yonsei medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gwang Sil KimDivision of Cardiology, Department of Internal Medicine, Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-5206-8187
Jongkwon SeoDivision of Cardiology, Department of Internal Medicine, Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-9179-1992
Byung Gyu KimDivision of Cardiology, Department of Internal Medicine, Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-5780-9642
Moo-Nyun JinDivision of Cardiology, Department of Internal Medicine, Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-5482-4441
Hye Young LeeDivision of Cardiology, Department of Internal Medicine, Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-3187-3667
Byung Ok KimDivision of Cardiology, Department of Internal Medicine, Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-7920-2750
Young Sup ByunDivision of Cardiology, Department of Internal Medicine, Sanggye Paik Hospital, Seoul, Korea. bbbyun@gmail.com.ORCID https://orcid.org/0000-0002-6360-6400

Funding

National Research Foundation of Korea 2019R1G1A1100442
6 · The paper itself

Abstract

purposeOnly a few Asian studies have discussed the impact of statin intensity on clinical outcomes in patients with peripheral artery disease (PAD). We aimed to investigate the clinical impact of statin intensity in patients with PAD after endovascular revascularization. MATERIALS AND

methodsFrom April 2009 to June 2019, 376 patients with lower extremity PAD treated with endovascular revascularization were enrolled. They were classified into three groups according to statin intensity: no-statin, low-to-moderate intensity (LMI), and high-intensity (HI). The primary outcomes were major adverse cardiovascular events (MACE) and major adverse limb events (MALE).

resultsDuring the 40-month follow-up, MACE occurred less frequently in the HI and LMI groups than the no-statin group (11.4% vs. 16.0% vs. 39%,

conclusionHI and LMI statin use is associated with a significant reduction in MACE events than no-statin use. HI statin use was associated with better MALE outcomes than no-statin or LMI statin use.

Indexed as

Hydroxymethylglutaryl-CoA Reductase InhibitorsPeripheral Arterial DiseaseHumansLower ExtremityProportional Hazards ModelsTreatment OutcomeHydroxymethylglutaryl-CoA Reductase Inhibitorsendovascular revascularizationmajor adverse cardiovascular eventPeripheral artery diseasestatin

Identifiers

PMID35352884
PMCPMC8965427

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.