Evidence map›Paper›PMID 35352882›Full record

ArticleYonsei medical journal2022

Stroke and Systemic Thromboembolism according to CHA

Kyung Bae Lee, Tae-Hoon Kim, Junbeom Park, Jin-Kyu Park, Ki-Woon Kang, Jun Kim, Hyung Wook Park, Eue-Keun Choi, Jin-Bae Kim, Young Soo Lee and 2 more

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Yonsei medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02786095 (Comparison Study of Drugs for Symptom Control and Complication Prevention of Atrial Fibrillation), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02786095 unknown statusnot on this map

Comparison Study of Drugs for Symptom Control and Complication Prevention of Atrial Fibrillation (AF) (Code-AF Trial)

TypeobservationalSponsorYonsei UniversityRan2016 to 2024Enrolled20,000ConditionsAtrial Fibrillation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kyung Bae Lee *Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7247-5959
Tae-Hoon Kim *Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4200-3456
Junbeom ParkDepartment of Cardiology, School of Medicine, Ewha Woman's University, Seoul, Korea.ORCID https://orcid.org/0000-0003-2192-9401
Jin-Kyu ParkDepartment of Cardiology, Hanyang University Seoul Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-7931-777X
Ki-Woon KangDivision of Cardiology, Eulji University Hospital, Daejeon, Korea.ORCID https://orcid.org/0000-0002-1361-0022
Jun KimHeart Institute, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3573-638X
Hyung Wook ParkDepartment of Cardiology, Chonnam National University Hospital, Chonnam National University School of Medicine, Gwangju, Korea.ORCID https://orcid.org/0000-0002-9630-0467
Eue-Keun ChoiDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-0411-6372
Jin-Bae KimDivision of Cardiology, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea.ORCID https://orcid.org/0000-0002-0293-0901
Young Soo LeeDivision of Cardiology, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0002-8229-8300
Jaemin ShimDivision of Cardiology, Department of Internal Medicine, Korea University Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-8251-1522
Boyoung JoungDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea. cby6908@yuhs.ac.ORCID https://orcid.org/0000-0001-9036-7225

Funding

Ministry of Health and Welfare HC19C0130Ministry of Health and Welfare HI15C1200Ministry of Health and Welfare HI19C0481
6 · The paper itself

Abstract

purposeThe incidence of stroke and/or systemic thromboembolism (SSE) has not been properly evaluated in well-anticoagulated atrial fibrillation (AF) patients. This study investigated the incidence of SSE according to CHA MATERIALS AND

methodsFrom the prospective multicenter COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation (CODE-AF) registry, we identified 9503 patients with non-valvular AF (mean age, 68±8 years; female 35.5%) enrolled between June 2016 and May 2020 with eligible follow-up visits. Stroke incidence in the CODE-AF registry was compared with that in an oral anticoagulant (OAC)-naïve AF cohort from the Korean National Health Insurance database.

resultsThe usage rates of OACs and antiplatelet agents were 73.5% (non-vitamin K OACs, 56.4%; warfarin, 17.1%) and 23.8%, respectively. During a mean follow-up period of 26.3±9.6 months, 163 (0.78 per 100 person-years) patients had SSE. The incidence rate (per 100 person-years) of SSE was 0.77 in the total population, 0.26 in low-risk patients [CHA

conclusionContemporary AF patients have a stroke rate about one-fifth that in OAC-naïve AF patients and exhibit different stroke risk factors. STUDY REGISTRATION: ClinicalTrials.gov (NCT02786095).

Indexed as

Atrial FibrillationStrokeThromboembolismAgedFemaleHumansMaleMiddle AgedProspective StudiesRepublic of KoreaRisk AssessmentAtrial fibrillationembolismriskstroke

Identifiers

PMID35352882
PMCPMC8965433

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.