Evidence map›Paper›PMID 35352759›Full record

ArticleRevista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria2022

Alterations in blood glucose concentration in wild rodents, Holochilus sciureus, naturally infected with Schistosoma mansoni.

João Gustavo Mendes Rodrigues, Maria Gabriela Sampaio Lira, Ranielly Araújo Nogueira, Gleycka Cristine Carvalho Gomes, Irlla Correia Lima Licá, Jeferson Kelvin Alves de Oliveira Silva, Guilherme Silva Miranda, Nêuton Silva-Souza

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

João Gustavo Mendes RodriguesPrograma de Pós-graduação em Parasitologia, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0003-0920-4977
Maria Gabriela Sampaio LiraPrograma de Pós-graduação em Ciências da Saúde, Universidade Federal do Maranhão - UFMA, São Luís, MA, Brasil.ORCID http://orcid.org/0000-0003-0380-2167
Ranielly Araújo NogueiraPrograma de Pós-graduação em Ciências da Saúde, Universidade Federal do Maranhão - UFMA, São Luís, MA, Brasil.ORCID http://orcid.org/0000-0002-9470-0918
Gleycka Cristine Carvalho GomesPrograma de Pós-graduação em Ciências da Saúde, Universidade Federal do Maranhão - UFMA, São Luís, MA, Brasil.ORCID http://orcid.org/0000-0002-9527-4009
Irlla Correia Lima LicáPrograma de Pós-graduação em Ciências da Saúde, Universidade Federal do Maranhão - UFMA, São Luís, MA, Brasil.ORCID http://orcid.org/0000-0003-4689-3863
Jeferson Kelvin Alves de Oliveira SilvaPrograma de Pós-graduação em Parasitologia, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0003-4194-7578
Guilherme Silva MirandaPrograma de Pós-graduação em Parasitologia, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0003-3763-2776
Nêuton Silva-SouzaDepartamento de Química e Biologia, Universidade Estadual do Maranhão - UEMA, São Luís, MA, Brasil.ORCID http://orcid.org/0000-0001-8912-017X
Universidade Federal do Maranhão · BRInstituto Federal de Educação, Ciência e Tecnologia de Minas Gerais · BRUniversidade do Estado de Minas Gerais · BRUniversidade Estadual do Maranhão · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to evaluate the changes in peripheral blood glucose concentrations induced by Schistosoma mansoni infection in Holochilus sciureus rodents, a wild reservoir of the parasite. Glucose concentration was measured in the plasma of blood samples using a colorimetric enzymatic test. Biological parameters and S. mansoni burden in each rodent were also verified and correlated with glucose concentrations. A total of 76 H. sciureus were captured, out of which 20 (26%) were infected with S. mansoni (n=13 males and n=7 females). Although the parasite burden was comparable between the sexes, blood glucose concentration was lower in infected males and almost unchanged in females. Furthermore, histopathological data revealed that male rodents had a greater hepatic granulomatous inflammatory reaction than females. In addition, we also confirmed that the weight and total length of the analyzed animals had no effect on glucose levels. Therefore, natural infection with S. mansoni in H. sciureus may have a lower impact on glycemic homeostasis in females, which will help us understand the role of these rodents as reservoirs of S. mansoni.

Indexed as

Schistosomiasis mansoniAnimalsBlood GlucoseFemaleMaleRodentiaSchistosoma mansoniSigmodontinaeBlood Glucose

Identifiers

PMID35352759
PMCPMC9901889
OpenAlexW4226186818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.