Evidence map›Paper›PMID 35352202›Full record

ArticleArchives of microbiology2022

Genome sequence of Corynebacterium amycolatum ICIS 99 isolated from human vagina reveals safety and beneficial properties.

Irina V Gladysheva, Yuriy A Khlopko, Sergey V Cherkasov, Vladimir Ya Kataev

Abstract read
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In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Irina V GladyshevaInstitute for Cellular and Intracellular Symbiosis UrB RAS, Orenburg, Russia. gladishevaiv@yandex.ru.ORCID http://orcid.org/0000-0001-6231-7028
Yuriy A KhlopkoInstitute for Cellular and Intracellular Symbiosis UrB RAS, Orenburg, Russia.ORCID http://orcid.org/0000-0002-2880-3214
Sergey V CherkasovInstitute for Cellular and Intracellular Symbiosis UrB RAS, Orenburg, Russia.ORCID http://orcid.org/0000-0002-4411-8620
Vladimir Ya KataevInstitute for Cellular and Intracellular Symbiosis UrB RAS, Orenburg, Russia.ORCID http://orcid.org/0000-0002-0707-2977
Institute of Cellular and Intracellular Symbiosis · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corynebacterium amycolatum ICIS 99 was isolated from vaginal smears of healthy women and showed promising results in antimicrobial screenings. Here, we report the draft genome sequence of this strain and analyze its main features to assess its safety and useful properties. The genome is 2,532,503 bp long and contains 2186 CDSs with an average G + C content of 59.0%. Analyses of the ICIS 99 genome revealed the absence of true virulence factors. The genome contains genes involved in the synthesis of secondary metabolites and bacteriocins of the class sactipeptide. In the genome of ICIS 99, we identified a large number of genes responsible for adaptation and survival in the vaginal environment, including acid and oxidative stress resistance genes. The genomic information of ICIS 99 provides a basis for understanding the safety and useful properties of ICIS 99 and for considering it as a potential probiotic strain. The whole genome shotgun project has been deposited at DDBJ/ENA/GenBank under the accession number JAIUSU000000000.

Indexed as

BacteriocinsCorynebacteriumBase CompositionFemaleHumansVaginaBacteriocinsCorynebacterium amycolatumDraft genome sequenceSecondary metabolitesVaginal microbiome

Identifiers

PMID35352202
OpenAlexW4225613012

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.