Evidence map›Paper›PMID 35352124›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022

Changes in Dietary Total and Nonheme Iron Intake Is Associated With Incident Frailty in Older Men: The Concord Health and Aging in Men Project.

Rebecca Luong, Rosilene V Ribeiro, Anna Rangan, Vasi Naganathan, Fiona Blyth, Louise M Waite, David J Handelsman, Robert G Cumming, David G Le Couteur, Vasant Hirani

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Rebecca LuongNutrition and Dietetics Group, Sydney Nursing School, Faculty of Medicine and Health, The University of Sydney, NSW, Australia.ORCID 0000-0001-9245-0321
Rosilene V RibeiroCharles Perkins Centre, The University of Sydney, NSW, Australia.
Anna RanganNutrition and Dietetics Group, Sydney Nursing School, Faculty of Medicine and Health, The University of Sydney, NSW, Australia.ORCID 0000-0003-1815-844X
Vasi NaganathanCentre for Education and Research on Ageing, Concord Hospital, The University of Sydney, Concord, NSW, Australia.ORCID 0000-0001-7243-0796
Fiona BlythARC Centre of Excellence in Population Ageing Research (CEPAR), The University of Sydney, NSW, Australia.
Louise M WaiteCentre for Education and Research on Ageing, Concord Hospital, The University of Sydney, Concord, NSW, Australia.
David J HandelsmanANZAC Research Institute, The University of Sydney and Concord Hospital, Concord, NSW, Australia.ORCID 0000-0002-4200-7476
Robert G CummingARC Centre of Excellence in Population Ageing Research (CEPAR), The University of Sydney, NSW, Australia.ORCID 0000-0002-0261-6103
David G Le CouteurCharles Perkins Centre, The University of Sydney, NSW, Australia.ORCID 0000-0002-4227-5817
Vasant HiraniNutrition and Dietetics Group, Sydney Nursing School, Faculty of Medicine and Health, The University of Sydney, NSW, Australia.
The University of Sydney · AU

Funding

Ageing and Alzheimers Research FoundationAgeing and Alzheimers Research InstituteAustralian Research Council Centre of Excellence in Population Ageing Research CE170100005National Health and Medical Research Council 301916Sydney Medical School Foundation
6 · The paper itself

Abstract

backgroundNutritional intake could influence the development of frailty. The aim was to evaluate the associations between dietary iron intakes and changes in dietary iron intakes with frailty.

methodsCross-sectional analyses involved 785 men with Fried frailty phenotype (FP) and 758 men with Rockwood frailty index (FI) data aged 75 years and older at nutrition assessment from the Concord Health and Ageing in Men Project prospective cohort study. Of these, 563 men who were FP robust or prefrail, and 432 men who were FI nonfrail were included in the longitudinal analyses for more than 3 years. Dietary intake was assessed at both timepoints using a validated diet history questionnaire. The dietary calculation was used to derive heme iron and nonheme iron intakes from total iron intakes. The associations were evaluated through binary logistic regression.

resultsIncidence of FP frailty was 15.3% (n = 86). In longitudinal analyses, maintaining total iron intakes (medium tertile -2.61-0.81 mg/d), increases in total iron and nonheme iron intakes (high tertiles ≥0.82 mg/d and ≥0.80 mg/d), and changes in nonheme iron intake (1 mg increment) were associated with reduced risks of incident FP frailty (OR: 0.47 [95% confindence interval (CI): 0.24, 0.93, p = .031], OR 0.48 [95% CI: 0.23, 0.99, p = .048], OR 0.41 [95% CI: 0.20, 0.88, p = .022], and OR 0.89 [95% CI: 0.82, 0.98, p = .017]).

conclusionMaintaining or increases in total dietary iron and increases or changes in dietary nonheme iron intakes more than 3 years were associated with reduced incidence of FP frailty in older men.

Indexed as

FrailtyAgedAgingCross-Sectional StudiesDietFrail ElderlyHumansIronIron, DietaryProspective StudiesIronIron, DietaryDietDietary ironFoodFrailty syndromeOld men

Identifiers

PMID35352124
PMCPMC9434472
OpenAlexW4221085123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.