Evidence map›Paper›PMID 35352122›Full record

ArticleGlycobiology2022

CarbArrayART: a new software tool for carbohydrate microarray data storage, processing, presentation, and reporting.

Yukie Akune, Sena Arpinar, Lisete M Silva, Angelina S Palma, Virginia Tajadura-Ortega, Kiyoko F Aoki-Kinoshita, René Ranzinger, Yan Liu, Ten Feizi

Abstract read
In one paragraph

Article in Glycobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yukie AkuneGlycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College, Du Cane Road, London W12 0NN, United Kingdom.ORCID 0000-0002-0839-0643
Sena ArpinarComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Rd, Athens, GA 30602, United States.
Lisete M SilvaGlycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College, Du Cane Road, London W12 0NN, United Kingdom.ORCID 0000-0003-4876-5240
Angelina S PalmaUCIBIO, Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.ORCID 0000-0001-5797-6555
Virginia Tajadura-OrtegaGlycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College, Du Cane Road, London W12 0NN, United Kingdom.
Kiyoko F Aoki-KinoshitaGlycan and Life Systems Integration Center (GaLSIC), Soka University, 1-236 Tangi-machi, Hachioji, Tokyo 192-8577, Japan.ORCID 0000-0002-6662-8015
René RanzingerComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Rd, Athens, GA 30602, United States.
Yan LiuGlycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College, Du Cane Road, London W12 0NN, United Kingdom.ORCID 0000-0002-2566-6867
Ten FeiziGlycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College, Du Cane Road, London W12 0NN, United Kingdom.ORCID 0000-0001-6495-0329

Funding

GlyGen Supplement: Develop automatic literature mining tool for extracting context specific glycan-protein data that will enhance the extent and quality of data in GlyGenU01GM125267 · NIGMS · UNIVERSITY OF GEORGIA · PI MAZUMDER, RAJA, TIEMEYER, MICHAEL · 2017 to 2021
$10.2M
NIGMS NIH HHS U01 GM125267Wellcome TrustWellcome Trust 108430/Z/15/ZWellcome Trust 218304/Z/19/ZWellcome Trust WT099197/Z/12/Z
6 · The paper itself

Abstract

Glycan microarrays are essential tools in glycobiology and are being widely used for assignment of glycan ligands in diverse glycan recognition systems. We have developed a new software, called Carbohydrate microArray Analysis and Reporting Tool (CarbArrayART), to address the need for a distributable application for glycan microarray data management. The main features of CarbArrayART include: (i) Storage of quantified array data from different array layouts with scan data and array-specific metadata, such as lists of arrayed glycans, array geometry, information on glycan-binding samples, and experimental protocols. (ii) Presentation of microarray data as charts, tables, and heatmaps derived from the average fluorescence intensity values that are calculated based on the imaging scan data and array geometry, as well as filtering and sorting functions according to monosaccharide content and glycan sequences. (iii) Data export for reporting in Word, PDF, and Excel formats, together with metadata that are compliant with the guidelines of MIRAGE (Minimum Information Required for A Glycomics Experiment). CarbArrayART is designed for routine use in recording, storage, and management of any slide-based glycan microarray experiment. In conjunction with the MIRAGE guidelines, CarbArrayART addresses issues that are critical for glycobiology, namely, clarity of data for evaluation of reproducibility and validity.

Indexed as

GlycomicsPolysaccharidesInformation Storage and RetrievalMicroarray AnalysisReproducibility of ResultsSoftwarePolysaccharidesglycan microarray data managementglycan microarray data presentationglycan microarray data storageglycan microarray softwareglycoinformatics

Identifiers

PMID35352122
PMCPMC9191619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.