Evidence map›Paper›PMID 35351930›Full record

ArticleScientific reports2022

Hydrogen phosphate selectively induces MDA MB 231 triple negative breast cancer cell death in vitro.

Aya Shanti, Kenana Al Adem, Cesare Stefanini, Sungmun Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aya ShantiDepartment of Biomedical Engineering, Healthcare Engineering Innovation Center, Khalifa University of Science and Technology, 127788, Abu Dhabi, United Arab Emirates.
Kenana Al AdemDepartment of Biomedical Engineering, Healthcare Engineering Innovation Center, Khalifa University of Science and Technology, 127788, Abu Dhabi, United Arab Emirates.
Cesare StefaniniDepartment of Biomedical Engineering, Healthcare Engineering Innovation Center, Khalifa University of Science and Technology, 127788, Abu Dhabi, United Arab Emirates.
Sungmun LeeDepartment of Biomedical Engineering, Healthcare Engineering Innovation Center, Khalifa University of Science and Technology, 127788, Abu Dhabi, United Arab Emirates. sung.lee@ku.ac.ae.
Khalifa University of Science and Technology · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphate ions are the most abundant anions inside the cells, and they are increasingly gaining attention as key modulators of cellular function and gene expression. However, little is known about the effect of inorganic phosphate ions on cancer cells, particularly breast cancer cells. Here, we investigated the toxicity of different phosphate compounds to triple-negative human breast cancer cells, particularly, MDA-MB-231, and compared it to that of human monocytes, THP-1. We found that, unlike dihydrogen phosphate (H

Indexed as

Triple Negative Breast NeoplasmsApoptosisCell Line, TumorHumansHydrogenPhosphatesHydrogenPhosphates

Identifiers

PMID35351930
PMCPMC8964734
OpenAlexW4220730194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.