Evidence map›Paper›PMID 35351903›Full record

ArticleNPJ breast cancer2022

Gene signatures in patients with early breast cancer and relapse despite pathologic complete response.

Simona Bruzas, Oleg Gluz, Nadia Harbeck, Peter Schmid, Javier Cortés, Jens Blohmer, Christine Seiberling, Ouafaa Chiari, Hakima Harrach, Beyhan Ataseven and 7 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 4 countries.

Simona BruzasInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.
Oleg GluzWest German Study Group, Moenchengladbach, Germany.
Nadia HarbeckBreast Center, Dept. OB&GYN and CCCLMU, University of Munich (LMU), Munich, Germany.ORCID http://orcid.org/0000-0002-9744-7372
Peter SchmidBarts Cancer Institute, Queen Mary University London, London, United Kingdom.
Javier CortésInternational Breast Cancer Centre (IBCC), Quiron Group, Barcelona, Spain.ORCID http://orcid.org/0000-0001-7623-1583
Jens BlohmerKlinik für Gynäkologie mit Brustzentrum, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Christine SeiberlingInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.
Ouafaa ChiariInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.ORCID http://orcid.org/0000-0002-6466-4717
Hakima HarrachInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.
Beyhan AtasevenInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.
Satyendra ShenoyInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.ORCID http://orcid.org/0000-0001-5159-0803
Mark H DysonInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.
Eugen TrautInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.
Ingo TheuerkaufInstitut für Pathologie Viersen, Viersen, Germany.
Daniel GebauerInstitut für Pathologie Viersen, Viersen, Germany.
Sherko KuemmelInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany.
Mattea ReinischInterdisciplinary Breast Unit, Kliniken Essen-Mitte, Essen, Germany. M.Reinisch@kem-med.com.ORCID http://orcid.org/0000-0002-1381-8595
Kliniken Essen-Mitte · DELVR-Klinik für Orthopädie Viersen · DEBethesda Hospital · INCharité - Universitätsmedizin Berlin · DELudwig-Maximilians-Universität München · DEMedSIR (Spain) · ESQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A substantial minority of early breast cancer (EBC) patients relapse despite their tumors achieving pathologic complete response (pCR) after neoadjuvant therapy. We compared gene expression (BC360; nCounter

Identifiers

PMID35351903
PMCPMC8964729
OpenAlexW4220815992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.