Evidence map›Paper›PMID 35351867›Full record

ArticleTranslational psychiatry2022

APOE-ε4 modulates the association among plasma Aβ

Dai Shi, Siwei Xie, Anqi Li, Qingyong Wang, Hongbo Guo, Ying Han, Huaxi Xu, Wen-Biao Gan, Lei Zhang, Tengfei Guo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. A novel eye-tracking digital marker outperforms plasma biomarkers in detecting cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
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  14. Association of Different Combinations ofInternational journal of general medicine · 2023
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Dai ShiDepartment of Cerebrovascular Disease, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Siwei XieInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China.
Anqi LiInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China.
Qingyong WangDepartment of Neurology, University of Chinese Academy of Sciences-Shenzhen Hospital, Shenzhen, 518107, China.
Hongbo GuoDepartment of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Ying HanDepartment of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, 100053, China.
Huaxi XuCenter for Brain Sciences, the First Affiliated Hospital of Xiamen University, Institute of Neuroscience, Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Xiamen University, Xiamen, 361000, China.
Wen-Biao GanInstitute of Neurological Diseases, Shenzhen Bay Laboratory, Shenzhen, 518132, China.
Lei ZhangDepartment of Cerebrovascular Disease, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Tengfei GuoInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China. tengfei.guo@szbl.ac.cn.ORCID http://orcid.org/0000-0003-2982-0865
Alzheimer’s Disease Neuroimaging Initiative
Shenzhen Bay Laboratory · CNSun Yat-sen University · CNCapital Medical University · CNFirst Affiliated Hospital of Xiamen University · CNPeking University · CNUniversity of Chinese Academy of Sciences · CNZhujiang Hospital · CN

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

Including apolipoprotein E-ε4 (APOE-ε4) status and older age into consideration may increase the accuracy of plasma Aβ

Indexed as

Alzheimer DiseaseCognitive DysfunctionVascular DiseasesAdultAgedApolipoprotein E4HumansNeuropsychological TestsApolipoprotein E4

Identifiers

PMID35351867
PMCPMC8964707
OpenAlexW4221003301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.