Evidence map›Paper›PMID 35351819›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)2022

Synaptic plasticity in hippocampal CA1 neurons of mice lacking inositol-1,4,5-trisphosphate receptor-binding protein released with IP

Jun-Ichi Goto, Satoshi Fujii, Hiroki Fujiwara, Katsuhiko Mikoshiba, Yoshihiko Yamazaki

Open access · diamondAbstract read
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jun-Ichi GotoDepartment of Physiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Satoshi FujiiDepartment of Physiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Hiroki FujiwaraDepartment of Physiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Katsuhiko MikoshibaLaboratory for Developmental Neurobiology, Center for Brain Science, Riken, Wako, Saitama 351-0198, Japan.
Yoshihiko YamazakiDepartment of Physiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Yamagata University · JPRIKEN Center for Brain Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In hippocampal CA1 neurons of wild-type mice, a short tetanus (15 or 20 pulses at 100 Hz) or a standard tetanus (100 pulses at 100 Hz) to a naive input pathway induces long-term potentiation (LTP) of the responses. Low-frequency stimulation (LFS; 1000 pulses at 1 Hz) 60 min after the standard tetanus reverses LTP (depotentiation [DP]), while LFS applied 60 min prior to the standard tetanus suppresses LTP induction (LTP suppression). We investigated LTP, DP, and LTP suppression of both field excitatory postsynaptic potentials and population spikes in CA1 neurons of mice lacking the inositol 1,4,5-trisphosphate (IP

Indexed as

TetanusAdenosylhomocysteinaseAnimalsCarrier ProteinsElectric StimulationHippocampusInositol 1,4,5-Trisphosphate ReceptorsLong-Term PotentiationMiceNeuronal PlasticityNeuronsAdenosylhomocysteinaseCarrier ProteinsInositol 1,4,5-Trisphosphate ReceptorsIRBIT protein, mouse

Identifiers

PMID35351819
PMCPMC8973391
OpenAlexW4220909069

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.