Evidence map›Paper›PMID 35351770›Full record

ArticleBMJ case reports2022

Pathological haemodynamics of a middle cerebral artery stenosis validated by computational fluid dynamics.

Katsuhiro Tanaka, Fujimaro Ishida, Satoru Tanioka, Hidenori Suzuki

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Katsuhiro TanakaNeurosurgery, Mie Chuo Medical Center, Tsu, Mie, Japan tk_0303_ns@yahoo.co.jp.ORCID http://orcid.org/0000-0002-5222-0019
Fujimaro IshidaNeurosurgery, Mie Chuo Medical Center, Tsu, Mie, Japan.
Satoru TaniokaNeurosurgery, Mie Chuo Medical Center, Tsu, Mie, Japan.
Hidenori SuzukiNeurosurgery, Faculty of Medicine, Mie University Graduate School, Tsu, Mie, Japan.
Mie Chuo Medical Center · JPMie University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial arterial stenosis (ICAS) is one of the important causes of ischaemic stroke. However, the treatment for ICAS is not optimised, including medical therapies, because the mechanisms are diverse. The authors report a case of severe middle cerebral arterial stenosis accompanied by a floating thrombus, which caused artery-to-artery cerebral emboli. The patient was successfully treated with multiple antithrombotics including an anticoagulant, and the thrombus disappeared. Local haemodynamics around the middle cerebral arterial stenosis was analysed by computational fluid dynamics (CFD) using the patient-specific model. CFD analysis demonstrated that thrombus formation occurred at the poststenotic area with severe stagnant flow, which was judged by both wall shear stress and shear rate less than the specific thresholds. These findings suggest that CFD may be useful to diagnose the risk of stagnant flow-induced thrombosis and to predict the effectiveness of anticoagulant agents to prevent distal embolisms in ICAS.

Indexed as

Brain IschemiaStrokeConstriction, PathologicHemodynamicsHumansHydrodynamicsMiddle Cerebral Arteryneuroimagingneurology (drugs and medicines)stroke

Identifiers

PMID35351770
PMCPMC8966504
OpenAlexW4220926603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.