Evidence map›Paper›PMID 35351731›Full record

ArticleBMJ open2022

LAMP4yaws:

Becca Louise Handley, Camila González-Beiras, Serges Tchatchouang, Laud Antony Basing, Kouadio Aboh Hugues, Mohammed Bakheit, Lisa Becherer, Christina Ries, Earnest Njih Tabah, Tania Crucitti and 19 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04753788 (Clinical Evaluation of a Loop-mediated Isothermal Amplification Test for Treponema Pallidum Pertenue), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04753788 completednot on this map

Clinical Evaluation of a Loop-mediated Isothermal Amplification Test for Treponema Pallidum Pertenue: A Diagnostic Tool to Support Yaws Eradication

TypeobservationalSponsorLondon School of Hygiene and Tropical MedicineRan2021 to 2024Enrolled563ConditionsYawsArmsPCR, LAMP
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Detection ofApplied and environmental microbiology · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 9 institutions in 7 countries.

Becca Louise HandleyClinical Research Department, London School of Hygiene and Tropical Medicine Faculty of Infectious and Tropical Diseases, London, UK rebecca.handley1@lshtm.ac.uk.ORCID 0000-0003-2208-8229
Camila González-BeirasDepartment of Infectious Diseases, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Serges TchatchouangCentre Pasteur du Cameroun, Yaounde, Cameroon.
Laud Antony BasingUniversity of Ghana Noguchi Memorial Institute for Medical Research, Accra, Greater Accra, Ghana.
Kouadio Aboh HuguesNational Program of African Trypanosomiasis Elimination, Abidjan, Côte d'Ivoire.
Mohammed BakheitMast Diagnostica GmbH, Reinfeld, Germany.
Lisa BechererIMTEK - Department of Microsystems Engineering, University of Freiburg, Freiburg im Breisgau, Germany.
Christina RiesInstitute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald - Insel Riems, Germany.
Earnest Njih TabahNational Buruli Ulcer, Leprosy, Yaws and Leishmaniasis Control Program, Ministry of Public Health, Yaounde, Centre Region, Cameroon.
Tania CrucittiExperimental Bacteriology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Nadine BorstIMTEK - Department of Microsystems Engineering, University of Freiburg, Freiburg im Breisgau, Germany.
Simone LüertInstitute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald - Insel Riems, Germany.
Sieghard FrischmannMast Diagnostica GmbH, Reinfeld, Germany.
Tamara HaerpferIMTEK - Department of Microsystems Engineering, University of Freiburg, Freiburg im Breisgau, Germany.
Emelie LandmannMast Diagnostica GmbH, Reinfeld, Germany.
Ivy AmanorUniversity of Ghana Noguchi Memorial Institute for Medical Research, Accra, Greater Accra, Ghana.
Aboubacar SyllaInstitut Pasteur de Cote d'Ivoire, Abidjan, Lagunes, Côte d'Ivoire.
Mireille S Kouamé-SinaInstitut Pasteur de Cote d'Ivoire, Abidjan, Lagunes, Côte d'Ivoire.
Jean P Ndzomo-NgonoCentre Pasteur du Cameroun, Yaounde, Cameroon.
Adingra TanoInstitut Pasteur de Cote d'Ivoire, Abidjan, Lagunes, Côte d'Ivoire.
Daniel ArhinfulUniversity of Ghana Noguchi Memorial Institute for Medical Research, Accra, Greater Accra, Ghana.
Patrick AwondoCentre Pasteur du Cameroun, Yaounde, Cameroon.
Solange Ngazoa KakouInstitut Pasteur de Cote d'Ivoire, Abidjan, Lagunes, Côte d'Ivoire.
Sara EyangohCentre Pasteur du Cameroun, Yaounde, Cameroon.
Kennedy Kwasi AddoNoguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana.
Emma Michele Harding-EschClinical Research Department, London School of Hygiene and Tropical Medicine Faculty of Infectious and Tropical Diseases, London, UK.ORCID 0000-0002-1432-8109
Sascha KnaufInstitute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald - Insel Riems, Germany.
Oriol MitjàDepartment of Infectious Diseases, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Michael MarksClinical Research Department, London School of Hygiene and Tropical Medicine Faculty of Infectious and Tropical Diseases, London, UK.ORCID 0000-0002-7585-4743
Institut Pasteur de Côte d'Ivoire · CICentre Pasteur du Cameroun · CMUniversity of Ghana · GHFriedrich-Loeffler-Institut · DELondon School of Hygiene & Tropical Medicine · GBUniversity of Freiburg · DEHospital Universitari Germans Trias i Pujol · ESInstitut Pasteur de Madagascar · MGUniversité de Dschang · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionYaws, caused by the bacterium METHODS AND ANALYSIS: The LAMP4yaws project is a cross-sectional, observational, diagnostic accuracy study of a combined ETHICS AND DISSEMINATION: We have received ethical approval from all relevant institutional and national ethical committees. All participants, or their parents or guardians, must provide written informed consent prior to study enrolment. Study results will be published in an open access journal and disseminated with partners and the World Health Organization. TRIAL REGISTRATION NUMBER: NCT04753788.

Indexed as

Haemophilus ducreyiSkin UlcerYawsCross-Sectional StudiesGhanaHumansMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesObservational Studies as TopicReal-Time Polymerase Chain ReactionTreponemaTreponema palliduminfectious diseases & infestationsmolecular diagnosticspublic healthtropical medicine

Identifiers

PMID35351731
PMCPMC8966536
OpenAlexW4220674157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.