ArticleBMJ open2022
Barriers and facilitators of successful deprescribing as described by older patients living with frailty, their informal carers and clinicians: a qualitative interview study.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Interventions for reducing anticholinergic medication burden in older adults-a systematic review and meta-analysis.Age and ageing · 2023Pooled it
- Integrating patient education on deprescribing into care delivery: Learnings from the Optimize pragmatic trial.Patient education and counseling · 2026Trial
- Factors associated with family caregivers' attitudes toward deprescribing in long-term care facilities: a cross-sectional study in South Korea.BMC geriatrics · 2026Article
- A consolidated framework for implementation research (CFIR) informed exploration of a primary care intervention to support deprescribing for problematic polypharmacy in older adults living with frailty (DEPPLOY) in England: a qualitative study.International journal of clinical pharmacy · 2026Article
- Hospital-initiated community pharmacist medication review post-discharge.Aging clinical and experimental research · 2026Article
- Functional Deprescribing: A Systems-Based Framework for Safe Medication Reduction.Integrative medicine (Encinitas, Calif.) · 2026Article
- Communication and Medication-Related Deprescribing for Healthcare Professionals: A Rapid Review of the Literature.Worldviews on evidence-based nursing · 2026Review
- Antiseizure medication discontinuation: A mixed-methods exploration of factors considered by patients when approaching decision-making.Epilepsy research · 2025Article
- Proactive Deprescribing Among Older Adults With Polypharmacy: Barriers and Enablers.Annals of family medicine · 2025Article
- Barriers and facilitators to implementing polypharmacy management frameworks: a theory based qualitative exploration of key stakeholders.International journal of clinical pharmacy · 2025Article
- Challenges of benzodiazepine deprescribing in elderly patients attending primary healthcare.Frontiers in pharmacology · 2025Article
- Understanding frailty: a qualitative study of older heart failure patients' frail experience and perceptions of healthcare professionals with frailty.BMC geriatrics · 2024Article
- Review
- eConsultation for Deprescribing Among Older Adults: Clinician Perspectives on Implementation Barriers and Facilitators.Journal of general internal medicine · 2024Article
- Impact of comprehensive medication reviews on potentially inappropriate medication discontinuation in Medicare beneficiaries.Journal of the American Geriatrics Society · 2024Article
- A quantitative study on the impact of a community falls pharmacist role, on medicines optimisation in older people at risk of falls.BMC geriatrics · 2024Article
- Multidisciplinary medication review during older patient hospitalization according to STOPP/START criteria reduces potentially inappropriate prescriptions: MoPIM cohort study.BMC geriatrics · 2024Article
- Deprescribing in older adults in a French community: a questionnaire study on patients' beliefs and attitudes.BMC geriatrics · 2024Article
- Considerations, barriers and enablers of deprescribing among healthcare professionals in Ogun State, Southwest, Nigeria: a cross-sectional survey.BMC health services research · 2024Article
- Clinician and Family Caregiver Perspectives on Deprescribing Chronic Disease Medications in Older Nursing Home Residents Near the End of Life.Drugs & aging · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo explore the barriers/facilitators to deprescribing in primary care in England from the perspectives of clinicians, patients living with frailty who reside at home, and their informal carers, drawing on the Theoretical Domains Framework to identify behavioural components associated with barriers/facilitators of the process.
designExploratory qualitative study.
settingGeneral practice (primary care) in England.
participants9 patients aged 65+ living with frailty who attended a consultation to reduce or stop a medicine/s. 3 informal carers of patients living with frailty. 14 primary care clinicians including general practitioners, practice pharmacists and advanced nurse practitioners.
methodsQualitative semistructured interviews took place with patients living with frailty, their informal carers and clinicians. Patients (n=9) and informal carers (n=3) were interviewed two times: immediately after deprescribing and 5/6 weeks later. Clinicians (n=14) were interviewed once. In total, 38 interviews were undertaken. Framework analysis was applied to manage and analyse the data.
results6 themes associated with facilitators and barriers to deprescribing were generated, respectively, with each supported by between two and three subthemes. Identified facilitators of deprescribing with patients living with frailty included shared decision-making, gradual introduction of the topic, clear communication of the topic to the patient and multidisciplinary working. Identified barriers of deprescribing included consultation constraints, patients' fear of negative consequences and inaccessible terminology and information.
conclusionsThis paper offers timely insight into the barriers and facilitators to deprescribing for patients living with frailty within the context of primary care in England. As deprescribing continues to grow in national and international significance, it is important that future deprescribing interventions acknowledge the current barriers and facilitators and their associated behavioural components experienced by clinicians, patients living with frailty and their informal carers to improve the safety and effectiveness of the process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.