Evidence map›Paper›PMID 35351238›Full record

Trial reportThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2022

QT prolongation in the STREAM Stage 1 Trial.

G Hughes, H Bern, C-Y Chiang, R L Goodall, A J Nunn, I D Rusen, S K Meredith

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The effect of anti-tuberculosis drug pharmacokinetics on QTc prolongation.International journal of antimicrobial agents · 2023
    Observational
  10. Clofazimine for the treatment of tuberculosis.Frontiers in pharmacology · 2023
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

G HughesMedical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, UK.
H BernMedical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, UK.
C-Y ChiangDivision of Pulmonary Medicine, Department of Internal Medicine, Wanfang Hospital, Taipei Medical University, Taipei, Taiwan, Division of Pulmonary Medicine, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, International Union Against Tuberculosis and Lung Disease (The Union), Paris, France.
R L GoodallMedical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, UK.
A J NunnMedical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, UK.
I D RusenResearch Division, Vital Strategies, New York, NY, USA.
S K MeredithMedical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, UK.
Medical Research Council · GBMRC Clinical Trials Unit at UCL · GBTaipei Medical University · TWUniversity College London · GBVital Strategies · US

Funding

Medical Research Council MR/J012513/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Long QT SyndromeTuberculosis, Multidrug-ResistantClofazimineElectrocardiographyHeart RateHumansMoxifloxacinClofazimineMoxifloxacin

Identifiers

PMID35351238
PMCPMC8982645
OpenAlexW4220799280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.