ArticleRespiratory research2022
Local nebulization of 1α,25(OH)
Article in Respiratory research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- The Therapeutic Efficacy of Inhaled Vitamin D3 Metabolites Initiated During the Acute Phase of Hypersensitivity Pneumonitis: An In Vivo Study.Molecules (Basel, Switzerland) · 2026Article
- Reconsidering Vitamin D Supplementation in Pulmonary Disease: The Case for Targeted Respiratory Delivery.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026Article
- Environmental modulators of vascular physiology and inflammation.Experimental physiology · 2026Review
- Early risk identification for recurrent wheezing in children with respiratory syncytial virus infections.American journal of translational research · 2025Article
- The Role and Clinical Significance of Vitamin D in Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2025Review
- Beneficial Impact of Inhaled 25(OH)-Vitamin D3 and 1,25(OH)2-Vitamin D3 on Pulmonary Response in the Murine Model of Hypersensitivity Pneumonitis.International journal of molecular sciences · 2024Article
- Vitamin D3 regulates PM-driven primary human neutrophil inflammatory responses.Scientific reports · 2023Article
- Effect of Vitamin D on the Proliferation and Barrier of Atrophic Vaginal Epithelial Cells.Molecules (Basel, Switzerland) · 2023Article
- Waterpipe smoke inhalation induces lung injury and aortic endothelial dysfunction in mice.Physiological research · 2023Article
- Protective effects of inhaled antioxidants against air pollution-induced pathological responses.Respiratory research · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundEvidence supports a critical role of vitamin D status on exacerbation in chronic obstructive pulmonary disease, indicating the need to avoid vitamin D deficiency in these patients. However, oral vitamin D supplementation is limited by the potential risk for hypercalcemia. In this study, we investigated if local delivery of vitamin D to the lungs improves vitamin D-mediated anti-inflammatory action in response to acute inflammation without inducing hypercalcemia.
methodsWe studied vitamin D sufficient (VDS) or deficient (VDD) mice in whom 1α,25(OH)
resultsLocal 1α,25(OH)
conclusionUnder normal levels of vitamin D, local 1α,25(OH)
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.