Evidence map›Paper›PMID 35351083›Full record

ArticleBMC surgery2022

Swab test in biological fluids as predictor of COVID-19 transmission risk during surgery: a prospective cross-sectional study from an Italian COVID center.

N Fabbri, A Pesce, A Ussia, F D'Urbano, S Pizzicotti, S Greco, C V Feo

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Letter to Editor: In response to existence of SARS-CoV-2 in the peritoneal fluid.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

N FabbriGeneral Surgery Unit, Azienda USL Di Ferrara, Via Valle Oppio, 2, Ferrara, Italy. n.fabbri@ausl.fe.it.ORCID http://orcid.org/0000-0001-7039-3717
A PesceGeneral Surgery Unit, Azienda USL Di Ferrara, Via Valle Oppio, 2, Ferrara, Italy.
A UssiaGeneral Surgery Unit, Azienda USL Di Ferrara, Via Valle Oppio, 2, Ferrara, Italy.
F D'UrbanoDepartment of Translational Medicine, Azienda Ospedaliero-Universitaria Di Ferrara, Ferrara, Italy.
S PizzicottiBiochemical Analysis Laboratory - Clinics and Microbiology, Azienda Ospedaliero-Universitaria Di Ferrara, Ferrara, Italy.
S GrecoDepartment of Translational Medicine, Azienda Ospedaliero-Universitaria Di Ferrara, Ferrara, Italy.
C V FeoGeneral Surgery Unit, Azienda USL Di Ferrara, Via Valle Oppio, 2, Ferrara, Italy.
Arcispedale Sant'Anna · ITAzienda Unità Sanitaria Locale di Ferrara · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe contamination of body fluids by Severe Acute Respiratory Syndrome Coronavirus 2 during surgery is current matter of debate in the scientific literature concerning CoronaVIrus Disease 2019. Surgical guidelines were published during the first wave of the COVID-19 pandemic and recommended to avoid laparoscopic surgery as much as possible, in fear that the chimney effect of high flow intraperitoneal gas escape during, and after, the procedure would increase the risk of viral transmission.

aimThe aim of this study was to evaluate the possibility of SARS-CoV-2 transmission during surgery by searching for viral RNA in serial samplings of biological liquids.

methodsThis is a single center prospective cross-sectional study. We used a real-time reverse transcriptase (RT) polymerase chain reaction (PCR) test to perform swab tests for the qualitative detection of nucleic acid from SARS-CoV-2 in abdominal fluids, during emergency surgery and on the first post-operative day. In the case of thoracic surgery, we performed a swab test of pleural fluids during chest drainage placement as well as on the first post-operative day.

resultsA total of 20 samples were obtained: 5 from pleural fluids, 13 from peritoneal fluids and two from biliary fluid. All 20 swabs performed from biological fluids resulted negative for SARS-CoV-2 RNA detection.

conclusionTo date, there is no scientific evidence of possible contagion by laparoscopic aerosolization of SARS-CoV-2, neither is certain whether the virus is effectively present in biological fluids.

Indexed as

COVID-19Cross-Sectional StudiesHumansPandemicsProspective StudiesRNA, ViralSARS-CoV-2RNA, ViralCOVID-19Operating roomsPandemicsSurgery

Identifiers

PMID35351083
PMCPMC8964243
OpenAlexW4226212605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.