SynthesisBMC geriatrics2022
The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review.
Synthesis in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Frailty affects prognosis in patients with colorectal cancer: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- Trial
- The association between hospital frailty risk score and adverse inpatient outcomes in older adults with colorectal cancer.British journal of cancer · 2026Article
- The use of frailty screening measures for predicting long-term survival outcomes in head and neck cancer: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Real-world treatment durability and pain management in older adults with metastatic castration-resistant prostate cancer.Journal of geriatric oncology · 2026Article
- Article
- Patterns of care in patients with asymptomatic stage IV colon cancer: A population-based analysis.Surgery · 2025Article
- Clinical Frailty Scale predicts overall survival after colon cancer surgery in people aged 80 years and older: A prospective multicentre observational study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Observational
- Analysis of frailty change trajectories and its risk factors in patients with gastrointestinal tumor surgery: a prospective observational longitudinal study.World journal of surgical oncology · 2025Observational
- Navigating the Surgical Pathway for Frail, Older Adults Undergoing Colorectal Surgery.Clinics in colon and rectal surgery · 2025Review
- Characterization of tongue coating microbiome from patients with colorectal cancer.Journal of oral microbiology · 2024Article
- Assessing Frailty in Gastrointestinal Cancer: Two Diseases in One?Current oncology reports · 2024Review
- Predictive value of frailty assessment tools in patients undergoing surgery for gastrointestinal cancer: An observational cohort study.World journal of gastrointestinal surgery · 2023Article
- The Impact of Frailty on Palliative Care Receipt, Emergency Room Visits and Hospital Deaths in Cancer Patients: A Registry-Based Study.Current oncology (Toronto, Ont.) · 2023Article
- Robotic surgery in elderly patients with colorectal cancer: Review of the current literature.World journal of gastrointestinal surgery · 2023Review
- Is Frailty a Good Predictor of Postoperative Complications in Elective Abdominal Surgery?-A Single-Center, Prospective, Observational Study.Journal of personalized medicine · 2023Article
- The Frailty Index and colon cancer: a 2-sample Mendelian-randomization study.Journal of gastrointestinal oncology · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFrailty is a complex multifactorial syndrome characterised by a significant increase in vulnerability and worsened health outcomes. Despite a range of proposed frailty screening measures, the prevalence and prognostic value of frailty in patients undergoing surgery for colorectal cancer is not clear.
aimThe aim of this present review was to examine the use of commonly employed frailty screening measures in patients undergoing surgery for colorectal cancer.
methodsA systematic search of PubMed and Medline was carried out to identify studies reporting the use of frailty screening tools or measures in patients undergoing surgery for colorectal cancer. The screening measure used and prevalence of frailty within the population were recorded. Outcomes of interest were the incidence of post-operative complications, 30-day mortality and overall survival.
resultsOf the 15 studies included (n = 97, 898 patients), 9 studies were retrospective and included patients aged 70 years or older (n = 96, 120 patients). 5 of 12 studies reported that frailty was independently associated with the incidence of post-operative complications. There was also evidence that frailty was independently associated with 30-day mortality (1 of 4 studies, n = 9, 252 patients) and long-term survival (2 of 3 studies, n = 1, 420 patients).
conclusionsFrailty was common in patients with colorectal cancer and the assessment of frailty may have prognostic value in patients undergoing surgery. However, the basis of the relationship between frailty and post-operative outcomes is not clear and merits further study.
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