Evidence map›Paper›PMID 35350867›Full record

ArticleThyroid : official journal of the American Thyroid Association2022

AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency.

Xiao-Hui Liao, Pablo Avalos, Oksana Shelest, Raz Ofan, Michael Shilo, Catherine Bresee, Shibi Likhite, Jean-Philippe Vit, Heike Heuer, Brian Kaspar and 5 more

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Year in Thyroidology: Basic Science.Thyroid : official journal of the American Thyroid Association · 2023
    Article
  9. Article
  10. Article
  11. Thyroid Hormone Transporters in Pregnancy and Fetal Development.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Xiao-Hui LiaoDepartment of Medicine, The University of Chicago, Chicago, Illinois, USA.
Pablo AvalosThe Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Oksana ShelestThe Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Raz OfanDepartment of Biotechnology Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Michael ShiloDepartment of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Catherine BreseeBiostatistics Core, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Shibi LikhiteThe Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Jean-Philippe VitThe Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0001-5057-8554
Heike HeuerDepartment of Endocrinology, Diabetes and Metabolism, University of Duisburg-Essen, Essen, Germany.
Brian KasparThe Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Kathrin MeyerThe Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Alexandra M DumitrescuDepartment of Medicine, The University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-2743-770X
Samuel RefetoffDepartment of Medicine, The University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-0164-8231
Clive N SvendsenThe Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Gad D VatineThe Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Cedars-Sinai Medical Center · USBen-Gurion University of the Negev · ILNationwide Children's Hospital · USUniversity of Chicago · USUniversity of Duisburg-Essen · DE

Funding

Mouse Sbp2 deficiency models the multi-system syndrome of human SBP2 defectsR01DK110322 · NIDDK · UNIVERSITY OF CHICAGO · PI DUMITRESCU, ALEXANDRA MIHAELA · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK110322
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Monocarboxylic Acid TransportersSymportersX-Linked Intellectual DisabilityAnimalsDependovirusDisease Models, AnimalMaleMiceMuscle HypotoniaMuscular AtrophyMutationSerogroupTriiodothyronineMonocarboxylic Acid TransportersSlc16a2 protein, mouseSymportersTriiodothyroninegene therapyMCT8thyroid hormone cell transport

Identifiers

PMID35350867
PMCPMC9469747
OpenAlexW4220730417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.