ArticleOpen medicine (Warsaw, Poland)2022
Evaluation of menstrual irregularities after COVID-19 vaccination: Results of the MECOVAC survey.
Article in Open medicine (Warsaw, Poland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05083065 (Evaluation of Menstrual Irregularities and Abnormal Uterine Bleeding After Covid-19 Vaccine), which is not on this map. Cited by 70 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Menstrual Irregularities and Abnormal Uterine Bleeding After Covid-19 Vaccine
Who cites it
70 citing papers in PubMed, 5 syntheses or guidelines pooled it, 142 citations in OpenAlex.
- Prevalence of menstrual alterations following COVID-19 vaccination: systematic review & meta-analysis.BMC women's health · 2024Pooled it
- Menstrual disorders following COVID-19 vaccination: a review using a systematic search.Frontiers in drug safety and regulation · 2024Pooled it
- COVID-19 vaccination and menstrual disorders among women: Findings from a meta-analysis study.Journal of infection and public health · 2023Pooled it
- Axes of social inequities in COVID-19 clinical trials: A systematic review.Frontiers in public health · 2023Pooled it
- Endocrine system after 2 years of COVID-19 vaccines: A narrative review of the literature.Frontiers in endocrinology · 2022Pooled it
- Abnormal uterine bleeding during the COVID-19 pandemic among reproductive-age women with and without HIV.BMC infectious diseases · 2026Article
- Article
- Menstrual Disorders Following Covid 19 Vaccination in Women of Reproductive Age and Post-Menopause. A Systematic Review.Health science reports · 2025Review
- Reporting rates of abnormal uterine bleeding after COVID-19 vaccination in South Korea.Frontiers in drug safety and regulation · 2025Article
- Network analysis of adverse event patterns following immunization with mRNA COVID-19 vaccines: real-world data from the European pharmacovigilance database EudraVigilance.Frontiers in medicine · 2025Article
- The Possible Mechanistic Basis of Individual Susceptibility to Spike Protein Injury.Advances in virology · 2025Review
- Relation Between COVID-19 Infection and Vaccine and Menstrual Cycle Changes of Portuguese Adolescents in Higher Education.Healthcare (Basel, Switzerland) · 2024Article
- The biological and psychological impact of the Coronavirus disease-19 pandemic on the characteristics of the menstrual cycle.Journal of the Turkish German Gynecological Association · 2024Article
- Menopause symptom prevalence in three post-COVID-19 syndrome clinics in England: A cross-sectional analysis.IJID regions · 2024Article
- Association between COVID-19 Vaccines and Menstrual Disorders: Retrospective Cohort Study of Women Aged 12-55 Years Old in Catalonia, Spain.International journal of environmental research and public health · 2024Article
- COVID-19 vaccination and menstrual disturbances: A prospective study from Pakistan.Pakistan journal of medical sciences · 2024Article
- The prevalence of menstrual changes in COVID-19 vaccinated women: A cross-sectional study.Preventive medicine reports · 2024Article
- The direct effect of SARS-CoV-2 virus vaccination on human ovarian granulosa cells explains menstrual irregularities.NPJ vaccines · 2024Article
- Menstrual Cycle Disturbances after COVID-19 Vaccination: A Cross-Sectional Study.International journal of fertility & sterility · 2024Article
- Anti-COVID-19 Vaccination Alters the Menstrual Cycle and Dose Accumulation Enhances the Effect.Medicina (Kaunas, Lithuania) · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated menstrual irregularities after the first and second doses of the COVID-19 vaccine. Women answered a customised online questionnaire (ClinicalTrial.gov ID: NCT05083065) aimed to assess the vaccine type, the phase of the menstrual cycle during which the vaccine was administered, the occurrence of menstrual irregularities after the first and second doses, and how long this effect lasted. We excluded women with gynaecological and non-gynaecological diseases, undergoing hormonal and non-hormonal treatments, in perimenopause or menopause, as well as those who had irregular menstrual cycles in the last 12 months before vaccine administration. According to our data analysis, approximately 50-60% of reproductive-age women who received the first dose of the COVID-19 vaccine reported menstrual cycle irregularities, regardless of the type of administered vaccine. The occurrence of menstrual irregularities seems to be slightly higher (60-70%) after the second dose. Menstrual irregularities after both the first and second doses of the vaccine were found to self-resolve in approximately half the cases within two months. Based on these results, we suggest to consider these elements during the counselling of women who receive the COVID-19 vaccine, letting them know about the potential occurrence of temporary and self-limiting menstrual cycle irregularities in the subsequent month(s).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.