Evidence map›Paper›PMID 35350815›Full record

ArticleOpen forum infectious diseases2021

Rapid Changes in Nasopharyngeal Antibiotic Resistance Gene Profiles After Short Courses of Antibiotics in a Pilot Study of Ambulatory Young Children.

Leigh M Howard, Keerti L Dantuluri, Nicole Soper, Isaac P Thomsen, Carlos G Grijalva

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leigh M HowardVanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0003-4301-7235
Keerti L DantuluriLevine Children's Hospital at Atrium Health, Charlotte, North Carolina, USA.
Nicole SoperVanderbilt University Medical Center, Nashville, Tennessee, USA.
Isaac P ThomsenVanderbilt University Medical Center, Nashville, Tennessee, USA.
Carlos G GrijalvaVanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0002-2329-7797

Funding

Functional Antibody Repertoire Against S. aureus Leukocidins after Invasive Human InfectionR01AI139172 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CROWE, JAMES E · 2019 to 2023
$3.5M
Mentoring in transmission of influenza and strategies for preventionK24AI148459 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GRIJALVA, CARLOS G · 2020 to 2024
$893k
Pneumococcal dynamics in the conjugate vaccine era: Addressing unanswered questionsK23AI141621 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HOWARD, LEIGH MEREDITH · 2019 to 2022
$736k
NIAID NIH HHS K23 AI141621NIAID NIH HHS K24 AI148459NIAID NIH HHS R01 AI139172
6 · The paper itself

Abstract

We quantified antibiotic resistance genes before and after short antibiotic courses in nasopharyngeal specimens from ambulatory children. Carriage of certain bacteria and resistance genes was common before antibiotics. After antibiotics, we observed substantial reductions in pneumococcal and

Indexed as

acute respiratory illnessantibiotic resistanceantibioticschildrenPneumococcusStaphylococcus

Identifiers

PMID35350815
PMCPMC8947223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.