Evidence map›Paper›PMID 35350774›Full record

ArticleFrontiers in chemistry2022

Platelet Membrane Biomimetic Nanoparticles Combined With UTMD to Improve the Stability of Atherosclerotic Plaques.

Jia Zhou, Chengcheng Niu, Biying Huang, Sijie Chen, Caigui Yu, Sheng Cao, Wenjing Pei, Ruiqiang Guo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  7. Article
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  9. Review
  10. How Advanced Is Nanomedicine for Atherosclerosis?International journal of nanomedicine · 2025
    Review
  11. Review
  12. Nano Delivery System for Atherosclerosis.Journal of functional biomaterials · 2024
    Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Jia ZhouDepartment of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, China.
Chengcheng NiuDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China.
Biying HuangDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China.
Sijie ChenDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China.
Caigui YuDepartment of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, China.
Sheng CaoDepartment of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, China.
Wenjing PeiDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China.
Ruiqiang GuoDepartment of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, China.
Central South University · CNRenmin Hospital of Wuhan University · CNSecond Xiangya Hospital of Central South University · CNUnited Imaging Healthcare (China) · CNUniversity of South China · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although research on the treatment of atherosclerosis has progressed recently, challenges remain in developing more effective, safer and transformative strategies for the treatment of atherosclerosis. Nanomaterials have recently played a unique role in many fields, including atherosclerosis treatment. Platelets are common component in the blood. Due to their inherent properties, platelets can target and adhere to atherosclerotic plaques. Ultrasound-targeted microbubble destruction (UTMD) shows great prospects in promoting the efficiency of drug delivery in treating solid tumors. In this study, we explored the possibility that UTMD assists platelet biomimetic rapamycin (RAP)-loaded poly (lactic-co-glycolic acid) (PLGA) nanoparticles (RAP@PLT NPs) in the treatment of atherosclerosis. The biomimetic nano-formulations exhibit better targeting ability to plaques when administered

Indexed as

atherosclerotic plaquesbiomimicking nanoparticlesplatelet membrane coatingrapamycin (RAP)ultrasound-targeted microbubble destruction (UTMD)

Identifiers

PMID35350774
PMCPMC8958035
OpenAlexW4220870656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.