Evidence map›Paper›PMID 35350606›Full record

ArticleACS central science2022

Natural-Product-Directed Catalytic Stereoselective Synthesis of Functionalized Fused Borane Cluster-Oxazoles for the Discovery of Bactericidal Agents.

Rajesh Varkhedkar, Fan Yang, Rakesh Dontha, Jianglin Zhang, Jiyong Liu, Bernhard Spingler, Stijn van der Veen, Simon Duttwyler

Abstract read
In one paragraph

Article in ACS central science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Nucleophilic Addition of Stabilized Phosphorus Ylides toMolecules (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Carboranes without Cage Carbons:Journal of the American Chemical Society · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rajesh VarkhedkarDepartment of Chemistry, Zhejiang University, 38 Zheda Road, 310027 Hangzhou, People's Republic of China.
Fan YangDepartment of Microbiology, and Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 866 Yuhangtang Road, 310058 Hangzhou, People's Republic of China.
Rakesh DonthaDepartment of Chemistry, Zhejiang University, 38 Zheda Road, 310027 Hangzhou, People's Republic of China.
Jianglin ZhangDepartment of Microbiology, and Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 866 Yuhangtang Road, 310058 Hangzhou, People's Republic of China.
Jiyong LiuDepartment of Chemistry, Zhejiang University, 38 Zheda Road, 310027 Hangzhou, People's Republic of China.
Bernhard SpinglerDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.ORCID https://orcid.org/0000-0003-3402-2016
Stijn van der VeenDepartment of Microbiology, and Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 866 Yuhangtang Road, 310058 Hangzhou, People's Republic of China.
Simon DuttwylerDepartment of Chemistry, Zhejiang University, 38 Zheda Road, 310027 Hangzhou, People's Republic of China.ORCID https://orcid.org/0000-0001-9851-4920

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification of an alternative chemical space in order to address the global challenge posed by emerging antimicrobial resistance is very much needed for the discovery of novel antimicrobial lead compounds. Boron clusters are currently being explored in drug discovery due to their unique steric and electronic properties. However, the challenges associated with the synthesis and derivatization techniques of these compounds have limited their utility in the rapid construction of a library of molecules for screening against various biological targets as an alternative molecular platform. Herein, we report a transition-metal-catalyzed regioselective direct B-H alkylation-annulation of the

Identifiers

PMID35350606
PMCPMC8949637

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.