Evidence map›Paper›PMID 35350554›Full record

ArticleBrain communications2022

Functional connectivity underlying cognitive and psychiatric symptoms in post-COVID-19 syndrome: is anosognosia a key determinant?

Philippe Voruz, Alexandre Cionca, Isabele Jacot de Alcântara, Anthony Nuber-Champier, Gilles Allali, Lamyae Benzakour, Marine Thomasson, Patrice H Lalive, Karl-Olof Lövblad, Olivia Braillard and 11 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Profiles of Individuals With Long COVID Reporting Persistent Cognitive Complaints.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Inflammatory predictors of Post-COVID fatigue.Brain, behavior, & immunity - health · 2025
    Article
  11. Review
  12. Review
  13. Long-COVID and postural orthostatic tachycardia syndrome: a preliminary comparison of neuropsychological performance.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 1 country.

Philippe VoruzClinical and Experimental Neuropsychology Laboratory, Faculty of Psychology, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-6796-8807
Alexandre CioncaClinical and Experimental Neuropsychology Laboratory, Faculty of Psychology, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-1910-9650
Isabele Jacot de AlcântaraClinical and Experimental Neuropsychology Laboratory, Faculty of Psychology, University of Geneva, Geneva, Switzerland.
Anthony Nuber-ChampierClinical and Experimental Neuropsychology Laboratory, Faculty of Psychology, University of Geneva, Geneva, Switzerland.
Gilles AllaliNeurology Department, Geneva University Hospitals, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-4455-6719
Lamyae BenzakourFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Marine ThomassonClinical and Experimental Neuropsychology Laboratory, Faculty of Psychology, University of Geneva, Geneva, Switzerland.
Patrice H LaliveNeurology Department, Geneva University Hospitals, Geneva, Switzerland.
Karl-Olof LövbladFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Olivia BraillardDivision and Department of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
Mayssam NehmeDivision and Department of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
Matteo CoenFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Jacques SerratriceFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Jérôme PuginFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Idris GuessousFaculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-0491-6089
Basile N LandisFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Dan AdlerDivision of Pulmonary Diseases, Geneva University Hospitals, Geneva, Switzerland.
Alessandra GriffaFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Dimitri Van De VilleFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Frédéric AssalNeurology Department, Geneva University Hospitals, Geneva, Switzerland.
Julie A PéronClinical and Experimental Neuropsychology Laboratory, Faculty of Psychology, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-6579-4011
University of Geneva · CHUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lack of awareness of cognitive impairment (i.e. anosognosia) could be a key factor for distinguishing between neuropsychological post-COVID-19 condition phenotypes. In this context, the 2-fold aim of the present study was to (i) establish the prevalence of anosognosia for memory impairment, according to the severity of the infection in the acute phase and (ii) determine whether anosognosic patients with post-COVID syndrome have a different cognitive and psychiatric profile from nosognosic patients, with associated differences in brain functional connectivity. A battery of neuropsychological, psychiatric, olfactory, dyspnoea, fatigue and quality-of-life tests was administered 227.07 ± 42.69 days post-SARS-CoV-2 infection to 102 patients (mean age: 56.35 years, 65 men, no history of neurological, psychiatric, neuro-oncological or neurodevelopmental disorder prior to infection) who had experienced either a mild (not hospitalized;

Indexed as

anosognosiafunctional connectivityMRIneuropsychological deficitspost-COVID syndrome

Identifiers

PMID35350554
PMCPMC8956133
OpenAlexW4226119919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.