Evidence map›Paper›PMID 35350553›Full record

ArticleBrain communications2022

Prediction and early biomarkers of cognitive decline in Parkinson disease and atypical parkinsonism: a population-based study.

David Bäckström, Gabriel Granåsen, Susanna Jakobson Mo, Katrine Riklund, Miles Trupp, Henrik Zetterberg, Kaj Blennow, Lars Forsgren, Magdalena Eriksson Domellöf

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  18. Observational
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  20. Parkinson's disease therapy: what lies ahead?Journal of neural transmission (Vienna, Austria : 1996) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

David BäckströmDepartment of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0002-4417-2475
Gabriel GranåsenEpidemiology and Global Health Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Susanna Jakobson MoDepartment of Radiation Sciences, Diagnostic Radiology and Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.
Katrine RiklundDepartment of Radiation Sciences, Diagnostic Radiology and Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.
Miles TruppDepartment of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0001-8095-053X
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0003-3930-4354
Kaj BlennowDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Lars ForsgrenDepartment of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden.
Magdalena Eriksson DomellöfDepartment of Psychology, Umeå University, Umeå, Sweden.
Umeå University · SESahlgrenska University Hospital · SEYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progression of cognitive decline is heterogeneous in the three most common idiopathic parkinsonian diseases: Parkinson disease, multiple system atrophy and progressive supranuclear palsy. The causes for this heterogeneity are not fully understood, and there are no validated biomarkers that can accurately identify patients who will develop dementia and when. In this population-based, prospective study, comprehensive neuropsychological testing was performed repeatedly in new-onset, idiopathic parkinsonism. Dementia was diagnosed until 10 years and participants (

Indexed as

cognitive declinedementiamultiple system atrophyParkinson diseaseprogressive supranuclear palsy

Identifiers

PMID35350553
PMCPMC8947320
OpenAlexW4226059246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.