ArticleCureus2022
Gaseous Microemboli in the Cardiopulmonary Bypass Circuit: Presentation of a Systematic Data Collection Protocol Applied at Istituto Cardiocentro Ticino.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Progress in Understanding Brain Injury After Cardiopulmonary Bypass in Cardiac Surgery: A Narrative Review.Reviews in cardiovascular medicine · 2026Review
- The effect of surgical field suction flow rate and venous reservoir levels on gaseous microemboli transmission⋆.The journal of extra-corporeal technology · 2026Article
- Perfusion practices and safety standards in Pakistan: Insights from a preliminary nationwide survey.The journal of extra-corporeal technology · 2025Article
- Delirium after Cardiac Surgery-A Narrative Review.Brain sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Air emboli are reported to enter the cardiovascular system during cardiac surgery despite air-bubble filters in the arterial line of the cardiopulmonary bypass (CPB). A potential association with stroke, covert cerebral insults and cognitive decline after cardiac surgery has been hypothesized. Although most of the previous studies failed to prove it, this hypothesis cannot be rejected because the situation in the operating room (OR) is multifactorial and complex. Therefore, rigorous and standardized protocols are needed to investigate sources, patterns, as well as effective quantity and volume of air embolism. We hereby present our protocol in detail for systematic data collection as a standard quality control measure at our center, where air bubbles in the cardiopulmonary bypass circuit are measured by a commercial bubble counter. We also show a preview of the type of information that can be obtained for future analysis. The eventual aim is to determine a potential association between air emboli and adverse postoperative outcomes, as well as to identify major sources of air bubbles generation and in the long run to find effective prevention strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.