Evidence map›Paper›PMID 35350302›Full record

ArticleFrontiers in plant science2022

Metabolic Engineering of Crocin Biosynthesis in

Oussama Ahrazem, Changfu Zhu, Xin Huang, Angela Rubio-Moraga, Teresa Capell, Paul Christou, Lourdes Gómez-Gómez

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Heterologous Biosynthesis of Crocin I inInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Synthesis of Crocin I and Crocin II by Multigene Stacking inInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Microbial fortification of pharmacological metabolites in medicinal plants.Computational and structural biotechnology journal · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Oussama AhrazemDepartamento de Ciencia y Tecnología Agroforestal y Genética, Instituto Botánico, Universidad de Castilla-La Mancha, Campus Universitario, Albacete, Spain.
Changfu ZhuDepartment of Plant Production and Forestry Science, University of Lleida-Agrotecnio Centre de Recerca en Agrotecnologia (CERCA) Center, Lleida, Spain.
Xin HuangDepartment of Plant Production and Forestry Science, University of Lleida-Agrotecnio Centre de Recerca en Agrotecnologia (CERCA) Center, Lleida, Spain.
Angela Rubio-MoragaDepartamento de Ciencia y Tecnología Agroforestal y Genética, Instituto Botánico, Universidad de Castilla-La Mancha, Campus Universitario, Albacete, Spain.
Teresa CapellDepartment of Plant Production and Forestry Science, University of Lleida-Agrotecnio Centre de Recerca en Agrotecnologia (CERCA) Center, Lleida, Spain.
Paul ChristouDepartment of Plant Production and Forestry Science, University of Lleida-Agrotecnio Centre de Recerca en Agrotecnologia (CERCA) Center, Lleida, Spain.
Lourdes Gómez-GómezDepartamento de Ciencia y Tecnología Agroforestal y Genética, Instituto Botánico, Universidad de Castilla-La Mancha, Campus Universitario, Albacete, Spain.
Universitat de Lleida · ESUniversity of Castilla-La Mancha · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crocins are high-value soluble pigments that are used as colorants and supplements, their presence in nature is extremely limited and, consequently, the high cost of these metabolites hinders their use by other sectors, such as the pharmaceutical and cosmetic industries. The carotenoid cleavage dioxygenase 2L (

Indexed as

apocarotenoidsbiotechnologycrocinsCsCCD2LNicotianasaffron

Identifiers

PMID35350302
PMCPMC8957871
OpenAlexW4221023729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.