Evidence map›Paper›PMID 35350236›Full record

ArticleCase reports in ophthalmology

A Sudden Rise of Patients with Acute Macular Neuroretinopathy during the COVID-19 Pandemic.

Maarten B Jalink, Inge H G Bronkhorst

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Acute macular neuroretinopathy: is the name still appropriate?Medical hypothesis, discovery & innovation ophthalmology journal · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Acute macular neuroretinopathy following Moderna COVID-19 vaccination.Journal of ophthalmic inflammation and infection · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. COVID-19 Related Acute Macular Neuroretinopathy (AMN): A Case Series.International medical case reports journal · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Maarten B JalinkDepartment of Ophthalmology, University Medical Center Utrecht, Utrecht, The Netherlands.
Inge H G BronkhorstDepartment of Ophthalmology, Jeroen Bosch Ziekenhuis, 's-Hertogenbosch, The Netherlands.
Jeroen Bosch Ziekenhuis · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this paper is to inform on the surge of cases of acute macular neuroretinopathy (AMN) - a rare disease characterized by the sudden onset of acute scotomas caused by ischemia of the retinal capillary plexus - during the COVID-19 pandemic. In 2021, during the COVID-19 pandemic, a sudden rise in patients with AMN was observed in our clinic. In this paper, 4 cases from a hospital in the south of the Netherlands are reported, all of which could directly be linked to a COVID-19 infection or vaccination against the corona virus. A search for similar cases in the PubMed database produced thirteen relevant reports, which revealed that a similar increase in cases of AMN, all linked to COVID-19, has been observed worldwide. Analysis of the literature revealed that AMN is seen more often during the pandemic and that AMN after COVID-19 happens at a significantly older age than typically reported. This is the largest case series of patients with AMN after COVID-19 infection or vaccination. With the ongoing pandemic and extensive vaccination programs, it is expected that cases of AMN will surge. It is important for ophthalmologists to be aware of this disease, especially since typical patient characteristics may differ.

Indexed as

Acute macular neuroretinopathyCOVID-19Vaccine

Identifiers

PMID35350236
PMCPMC8921888
OpenAlexW4212839967

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.