Evidence map›Paper›PMID 35350195›Full record

ArticlebioRxiv : the preprint server for biology2022

Humoral and cellular immune memory to four COVID-19 vaccines.

Zeli Zhang, Jose Mateus, Camila H Coelho, Jennifer M Dan, Carolyn Rydyznski Moderbacher, Rosa Isela Gálvez, Fernanda H Cortes, Alba Grifoni, Alison Tarke, James Chang and 8 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 75 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 1 institution in 2 countries.

Zeli Zhang
Jose Mateus
Camila H Coelho
Jennifer M Dan
Carolyn Rydyznski Moderbacher
Rosa Isela Gálvez
Fernanda H Cortes
Alba Grifoni
Alison Tarke
James Chang
E Alexandar Escarrega
Christina Kim
Benjamin Goodwin
Nathaniel I Bloom
April Frazier
Daniela Weiskopf
Alessandro Sette
Shane Crotty
La Jolla Institute for Immunology · US

Funding

UC San Diego RAPID Faculty Development Program in Infectious DiseasesR25AI147376 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ADRIANA H TREMOULET, Joann Trejo · 2020 to 2026
$2.5M
NIAID NIH HHS R25 AI147376
6 · The paper itself

Abstract

Multiple COVID-19 vaccines, representing diverse vaccine platforms, successfully protect against symptomatic COVID-19 cases and deaths. Head-to-head comparisons of T cell, B cell, and antibody responses to diverse vaccines in humans are likely to be informative for understanding protective immunity against COVID-19, with particular interest in immune memory. Here, SARS-CoV-2-spike-specific immune responses to Moderna mRNA-1273, Pfizer/BioNTech BNT162b2, Janssen Ad26.COV2.S and Novavax NVX-CoV2373 were examined longitudinally for 6 months. 100% of individuals made memory CD4

Identifiers

PMID35350195
PMCPMC8963692
OpenAlexW4221017555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.