Evidence map›Paper›PMID 35350187›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Basal-Like Cell-Conditioned Medium Exerts Anti-Fibrotic Effects

Petra Khan, Kleanthis Fytianos, Sabrina Blumer, Julien Roux, Amiq Gazdhar, Spasenija Savic, Lars Knudsen, Danny Jonigk, Mark P Kuehnel, Sofia Mykoniati and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Scar wars: the viral menace.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Regeneration-Associated Transitional State Cells in Pulmonary Fibrosis.International journal of molecular sciences · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Petra KhanDepartment of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Kleanthis FytianosDepartment of Pulmonary Medicine, University Hospital Bern, and Department of Biomedical Research, University of Bern, Bern, Switzerland.
Sabrina BlumerDepartment of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Julien RouxDepartment of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Amiq GazdharDepartment of Pulmonary Medicine, University Hospital Bern, and Department of Biomedical Research, University of Bern, Bern, Switzerland.
Spasenija SavicInstitute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.
Lars KnudsenInstitute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.
Danny JonigkBiomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.
Mark P KuehnelBiomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.
Sofia MykoniatiDepartment of Internal Medicine, Jura Cantonal Hospital, Delemont, Switzerland.
Michael TammDepartment of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Thomas GeiserDepartment of Pulmonary Medicine, University Hospital Bern, and Department of Biomedical Research, University of Bern, Bern, Switzerland.
Katrin E HostettlerDepartment of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
University of Basel · CHGerman Center for Lung Research · DEUniversity Hospital of Bern · CHCABI Switzerland · CHUniversity Hospital of Basel · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In idiopathic pulmonary fibrosis (IPF), basal-like cells are atypically present in the alveolar region, where they may affect adjacent stromal cells by paracrine mechanisms. We here aimed to confirm the presence of basal-like cells in peripheral IPF lung tissue

Indexed as

aberrant basaloid cellsbasal cellsconditioned mediumidiopathic pulmonary fibrosislung fibroblastsPGE2

Identifiers

PMID35350187
PMCPMC8957873
OpenAlexW4220765078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.