ReviewFrontiers in bioengineering and biotechnology2022
Biosynthetic Pathway and Metabolic Engineering of Succinic Acid.
Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- β-cyclodextrin and succinic acid-driven metabolic enhancement of lipid, phycobiliprotein, and exopolysaccharide production in Porphyridium purpureum.Bioprocess and biosystems engineering · 2026Article
- Perspectives for Advancing Biotechnological Succinic Acid Production.Microbial biotechnology · 2026Review
- Metabolic rewiring for enhanced itaconate yield through heterotrophic COJournal of biological engineering · 2026Article
- Enhancing succinic acid production from lignocellulosic hydrolysates via reductive TCA pathway engineering in Klebsiella oxytoca.Bioprocess and biosystems engineering · 2026Article
- Effective energy harvesting of Yak by regulating the glucose and lipid metabolism in liver to adapt to the plateau environment.Scientific reports · 2025Article
- Assessing the effect of temperature drop on a stable anaerobic fermentation for volatile fatty acids production.Bioengineered · 2025Article
- Enhancing multi-season wheat yield through plant growth-promoting rhizobacteria using consortium and individual isolate applications.Folia microbiologica · 2025Article
- Nutritional Quality Fingerprinting of Wild and FarmedBiology · 2025Article
- Metabolomics Analysis of the Spoilage Characteristics ofFoods (Basel, Switzerland) · 2025Article
- Rising trend in the microbial fermentation for succinic acid production: a comprehensive overview on innovative approaches using versatile biological sources.Archives of microbiology · 2025Review
- EngineeringJournal of microbiology and biotechnology · 2025Article
- Targeting Mitochondrial Dysfunction in Cerebral Ischemia: Advances in Pharmacological Interventions.Antioxidants (Basel, Switzerland) · 2025Review
- Novel dose- and time-dependent toxicity biomarkers of fentanyl/carfentanyl: uncovered by urine-plasma metabolomics for forensics.Current research in toxicology · 2025Article
- Production of Succinic Acid by Metabolically EngineeredJournal of microbiology and biotechnology · 2024Article
- Genetic optimization of the human gut bacterium Phocaeicola vulgatus for enhanced succinate production.Applied microbiology and biotechnology · 2024Article
- Production of succinate with two COMicrobial cell factories · 2024Article
- Recent advances in bio-based production of top platform chemical, succinic acid: an alternative to conventional chemistry.Biotechnology for biofuels and bioproducts · 2024Review
- Succinic acid - A run-through of the latest perspectives of production from renewable biomass.Heliyon · 2024Review
- Separation and purification of nylon 54 salts from fermentation broth by an integrated process involving microfiltration, ultrafiltration, and ion exchange.Frontiers in bioengineering and biotechnology · 2024Article
- Elucidating the causal links between plasma and cerebrospinal fluid metabolites and pituitary tumors: a Mendelian randomization analysis.Frontiers in endocrinology · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Succinic acid, a dicarboxylic acid produced as an intermediate of the tricarboxylic acid (TCA) cycle, is one of the most important platform chemicals for the production of various high value-added derivatives. As traditional chemical synthesis processes suffer from nonrenewable resources and environment pollution, succinic acid biosynthesis has drawn increasing attention as a viable, more environmentally friendly alternative. To date, several metabolic engineering approaches have been utilized for constructing and optimizing succinic acid cell factories. In this review, different succinic acid biosynthesis pathways are summarized, with a focus on the key enzymes and metabolic engineering approaches, which mainly include redirecting carbon flux, balancing NADH/NAD
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.