Evidence map›Paper›PMID 35350131›Full record

ArticleJAC-antimicrobial resistance2022

Rafael Canton, Kamal Hamed, Tatiana Wiktorowicz, Nowel Redder, Noelle Jemmely, Juan Quevedo, Anne Santerre Henriksen

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Ceftobiprole activity against multidrug-resistantAntimicrobial agents and chemotherapy · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rafael CantonServicio de Microbiología, Hospital Universitario Ramón y Cajal, Madrid, Spain.ORCID https://orcid.org/0000-0003-1675-3173
Kamal HamedBasilea Pharmaceutica International Ltd, Basel, Switzerland.ORCID https://orcid.org/0000-0003-1896-9736
Tatiana WiktorowiczBasilea Pharmaceutica International Ltd, Basel, Switzerland.
Nowel RedderADVANZ PHARMA Switzerland, Sàrl, Geneva, Switzerland.
Noelle JemmelyADVANZ PHARMA Switzerland, Sàrl, Geneva, Switzerland.
Juan QuevedoADVANZ PHARMA Switzerland, Sàrl, Geneva, Switzerland.
Anne Santerre HenriksenMaxel Consulting ApS, Jyllinge, Denmark.ORCID https://orcid.org/0000-0002-7294-6386

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the susceptibility to ceftobiprole of clinical bacterial isolates obtained from hospitalized patients in Europe. Methods: A total of 20 000 non-duplicate bacterial isolates were collected in 2016-19 from patients with documented infections at medical centres located in 17 countries in Europe. Bacterial identification was confirmed and susceptibility to ceftobiprole and comparator agents was tested using the EUCAST broth microdilution methodology and interpretive criteria by a central microbiology laboratory. Results: Of the 20 000 isolates, 10 007 (50.0%) were Gram-positive and 9993 (50.0%) were Gram-negative. The most common species was Conclusions: Ceftobiprole continues to exhibit potent and broad-spectrum activity against Gram-positive and Gram-negative clinical isolates from Europe, and as expected, with a slight north-to-south and west-to-east susceptibility gradient.

Identifiers

PMID35350131
PMCPMC8947215

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.