Evidence map›Paper›PMID 35350030›Full record

ArticleRespiration; international review of thoracic diseases2022

Robotic Navigational Bronchoscopy Combined with Needle-Based Confocal Laser Endomicroscopy: Case Report of a Novel Approach to Diagnose Small Lung Nodules.

Christopher Manley, Tess Kramer, Rohit Kumar, Yulan Gong, Hormoz Ehya, Peter I Bonta, Jouke Annema

Open access · bronzeAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Respiration; international review of thoracic diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Two-phase radial endobronchial ultrasound bronchoscopy registration.Journal of medical imaging (Bellingham, Wash.) · 2025
    Article
  4. Article
  5. The role of confocal laser endomicroscopy in pulmonary medicine.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  6. Robotic Bronchoscopy: Review of Three Systems.Life (Basel, Switzerland) · 2023
    Review
  7. Robotic Assisted Bronchoscopy: The Ultimate Solution for Peripheral Pulmonary Nodules?Respiration; international review of thoracic diseases · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Christopher ManleyDepartment of Pulmonary and Critical Care, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Tess KramerDepartment of Respiratory Medicine, Amsterdam UMC, Amsterdam, The Netherlands.
Rohit KumarDepartment of Pulmonary and Critical Care, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Yulan GongDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Hormoz EhyaDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Peter I BontaDepartment of Respiratory Medicine, Amsterdam UMC, Amsterdam, The Netherlands.
Jouke AnnemaDepartment of Respiratory Medicine, Amsterdam UMC, Amsterdam, The Netherlands.
Fox Chase Cancer Center · USAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer-related death. Advancements in navigational bronchoscopy have shown encouraging results but the diagnostic yield of small lung nodules by bronchoscopic techniques is still below that of transthoracic needle aspiration. The development of robotic bronchoscopy has demonstrated a significantly improved navigational success but the diagnostic yield is regularly limited by near-miss of the target nodule. Needle-based confocal laser endomicroscopy is a novel imaging technique that allows for the real-time visualization of individual cells and structures with microscopic resolution at the tip of the needle. We present the first reported case of confocal laser endomicroscopy guided robotic bronchoscopy for the real-time diagnosis of a small, partially cystic lung nodule.

Indexed as

Lung NeoplasmsRobotic Surgical ProceduresSolitary Pulmonary NoduleBronchoscopyHumansLasersLungBiopsyConfocal microscopyLung cancerPulmonary noduleRobotic bronchoscopy

Identifiers

PMID35350030
OpenAlexW4220965264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.