ArticleJournal of clinical laboratory analysis2022
A case of ovarian Teratoma with nephroblastoma presenting abdomen metastasis.
Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Wilms' Tumor: A Review of Clinical Characteristics, Treatment Advances, and Research Opportunities.Medicina (Kaunas, Lithuania) · 2025Review
- Teratoma-associated and so-called pure Wilms tumour of the ovary represent two separate tumour types with distinct molecular features.Histopathology · 2024Article
- A case of immature teratoma with nephroblastic components in the oral cavity of a cat.The Journal of veterinary medical science · 2023Article
- Testicular teratoma with nephroblastoma in an adult - case report and literature review.Contemporary oncology (Poznan, Poland) · 2023Article
- A case of ovarian Teratoma with nephroblastoma presenting abdomen metastasis.Journal of clinical laboratory analysis · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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Abstract
backgroundTeratoma with nephroblastoma (TWN) is an extremely rare condition. Since 1984, only 45 reported cases have been identified. To our knowledge, there have been only two cases of TWN of ovarian origin. CASE PRESENTATION: We described a case of ovarian TWN who presented to us with painless abdominal masses 6 months after undergoing right ovarian cystectomy. The tumor had spread to the abdomen due to spontaneous rupture of the ovarian cyst and failure to undergo chemotherapy. Microscopically, the ovarian mass exhibited the typical components of a mature cystic teratoma. The tumors found in both the ovary and abdomen contained the nephroblastoma components and were strongly positive for WT-1. The patient was advised to undergo chemotherapy and she was lost to follow-up.
conclusionA careful histological examination is necessary for an accurate diagnosis, which is based on morphology and extensive immunohistochemical studies. According to the literature, surgical excision alone seems reasonable as the prognosis of TWN is considered to be good. However, due to the spontaneous rupture of the ovarian cyst, chemotherapy of the patient after the first surgery was necessary in our case. Therefore, additional case studies are needed to clarify the standardized treatment of TWN.
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