Evidence map›Paper›PMID 35349694›Full record

ArticleMicroscopy (Oxford, England)2022

Effects of aging on basement membrane of tibialis anterior muscle during recovery following muscle injury in rats.

Yuji Kanazawa, Mamoru Nagano, Satoshi Koinuma, Shinichi Sugiyo, Yasufumi Shigeyoshi

Open access · bronzeAbstract read
In one paragraph

Article in Microscopy (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Differential transcriptomic profiling of lipid metabolism and collagen remodeling in fast- and slow-twitch skeletal muscles in aging.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. Article
  6. Effects of Aging on Collagen in the Skeletal Muscle of Mice.International journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuji KanazawaDepartment of Medical Technology and Clinical Engineering, Hokuriku University, Kanazawa 920-1180, Japan.
Mamoru NaganoDepartment of Anatomy and Neurobiology, Graduate School of Medical Sciences, Kindai University, Ohnohigashi, Osakasayama 589-8511, Japan.
Satoshi KoinumaDepartment of Anatomy and Neurobiology, Graduate School of Medical Sciences, Kindai University, Ohnohigashi, Osakasayama 589-8511, Japan.
Shinichi SugiyoDepartment of Physical Therapy, Osaka University of Human Sciences, Shojyaku, Settsu 566-8501, Japan.
Yasufumi ShigeyoshiDepartment of Anatomy and Neurobiology, Graduate School of Medical Sciences, Kindai University, Ohnohigashi, Osakasayama 589-8511, Japan.
Kindai University · JPOsaka University of Human Sciences · JP

Funding

Hokuriku University Special Research Grant
6 · The paper itself

Abstract

We investigated the effect of aging on the basement membrane (BM) during postinjury muscle recovery. Using a rat model, we found that aging delayed muscle fiber and BM recovery. In addition, expression of BM-related factors peaked 7 days after muscle injury among both young and older rats. Peak expression of collagen IV synthetic factors decreased with age, whereas expression of the degradative factor was unaffected by age. These results suggest that age-related delays in postinjury muscle fiber and BM recovery may be related to the suppression of collagen IV synthetic factors.

Indexed as

AgingMuscle, SkeletalAnimalsBasement MembraneCollagenMuscle Fibers, SkeletalRatsCollagenagingbasement membranecollagen IVmuscle injuryrecoveryskeletal muscle

Identifiers

PMID35349694
PMCPMC9340794
OpenAlexW4221078358

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.