SynthesisDiabetes care2022
The Incidence of Adult-Onset Type 1 Diabetes: A Systematic Review From 32 Countries and Regions.
Synthesis in Diabetes care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06006468 (Evaluating ImmuNe Changes in the Evolution of Pre Type 1 Diabetes With Adult Onset), which is not on this map. Cited by 70 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating ImmuNe Changes in the Evolution of Pre Type 1 Diabetes With Adult Onset
Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic evidence for the causal association between type 1 diabetes and the risk of polycystic ovary syndrome.Human genomics · 2023Pooled it
- Combination therapy with saxagliptin and vitamin D for the preservation of β-cell function in adult-onset type 1 diabetes: a multi-center, randomized, controlled trial.Signal transduction and targeted therapy · 2023Trial
- Age of Type 1 Diabetes Onset and Dementia Risk: A Swedish Nationwide, Register-Based Cohort Study.Diabetes, obesity & metabolism · 2026Article
- Economic Burden of Type 1 Diabetes in France.Diabetes, obesity & metabolism · 2026Article
- Lifestyle and environmental risk factors for adult-onset autoimmune diabetes: current evidence and future directions.Diabetologia · 2026Review
- International consensus guidance for general population screening for islet autoantibodies to diagnose early-stage type 1 diabetes: a nominal group technique process.Diabetologia · 2026Article
- Acute-onset autoimmune type 1 diabetes presenting with diabetic ketoacidosis in an obese adult.Proceedings (Baylor University. Medical Center) · 2026Article
- Magnesium and Diabetes: A Review of Recent Studies on the Efficacy of Supplementation with Mg in Humans Suffering from This Chronic Metabolic Disease.International journal of molecular sciences · 2026Review
- Prevalence, incidence, mortality, and years of life lost to diabetes from 1996 to 2024 in Denmark.BMJ open diabetes research & care · 2026Article
- Differences in Clinical Manifestations and Islet Autoantibodies by Age in Adult-Onset Type 1 Diabetes.Diabetes care · 2026Article
- Identification of Different Age-at-Diagnosis-Based Endotypes and Clinical Phenotypes in a Cohort of Adult Patients Diagnosed with Type 1 Diabetes.Journal of clinical medicine · 2026Article
- Tubed or tubeless insulin pumps? A retrospective real-world analysis of national French health data.BMJ open diabetes research & care · 2026Article
- Article
- Methodological considerations in geriatric type 1 diabetes research.Acta diabetologica · 2026Article
- Experiences of Adults With Type 1 Diabetes Using Digital Health Technology for Diabetes Self-Care: Qualitative Study.JMIR diabetes · 2026Article
- Clinical, immunogenetic and metabolic characteristics of autoantibody-negative and autoantibody-positive type 1 diabetes.Diabetologia · 2026Article
- A 15-year registry based follow up study of site specific cancer mortality among immigrants with type 2 diabetes in Sweden.Scientific reports · 2026Article
- Article
- Psychosocial support for adult-onset type 1 diabetes: the living with and adapting to type 1 diabetes programme - a cross-national feasibility study.Frontiers in clinical diabetes and healthcare · 2026Article
- Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe epidemiology of adult-onset type 1 diabetes (T1D) incidence is not well-characterized due to the historic focus on T1D as a childhood-onset disease. PURPOSE: We assess the incidence of adult-onset (≥20 years) T1D, by country, from available data. DATA SOURCES: A systematic review of MEDLINE, Embase, and the gray literature, through 11 May 2021, was undertaken. STUDY SELECTION: We included all population-based studies reporting on adult-onset T1D incidence and published from 1990 onward in English. DATA EXTRACTION: With the search we identified 1,374 references of which 46 were included for data extraction. Estimates of annual T1D incidence were allocated into broad age categories (20-39, 40-59, ≥60, or ≥20 years) as appropriate. DATA SYNTHESIS: Overall, we observed the following patterns: 1) there is a paucity of data, particularly in low- and middle-income countries; 2) the incidence of adult-onset T1D is lowest in Asian and highest in Nordic countries; 3) adult-onset T1D is higher in men versus women; 4) it is unclear whether adult-onset T1D incidence declines with increasing age; and 5) it is unclear whether incidence of adult-onset T1D has changed over time. LIMITATIONS: Results are generalizable to high-income countries, and misclassification of diabetes type cannot be ruled out.
conclusionsFrom available data, this systematic review suggests that the incidence of T1D in adulthood is substantial and highlights the pressing need to better distinguish T1D from T2D in adults so that we may better assess and respond to the true burden of T1D in adults.
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