Evidence map›Paper›PMID 35349402›Full record

ArticleEmerging infectious diseases2022

Estimating Relative Abundance of 2 SARS-CoV-2 Variants through Wastewater Surveillance at 2 Large Metropolitan Sites, United States.

Alexander T Yu, Bridgette Hughes, Marlene K Wolfe, Tomas Leon, Dorothea Duong, Angela Rabe, Lauren C Kennedy, Sindhu Ravuri, Bradley J White, Krista R Wigginton and 2 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander T Yu
Bridgette Hughes
Marlene K Wolfe
Tomas Leon
Dorothea Duong
Angela Rabe
Lauren C Kennedy
Sindhu Ravuri
Bradley J White
Krista R Wigginton
Alexandria B Boehm
Duc J Vugia

Funding

ACL HHS U01CK000539NCEZID CDC HHS U01 CK000539
6 · The paper itself

Abstract

Monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) is critical for public health management of coronavirus disease. Sequencing is resource-intensive and incompletely representative, and not all isolates can be sequenced. Because wastewater SARS-CoV-2 RNA concentrations correlate with coronavirus disease incidence in sewersheds, tracking VOCs through wastewater is appealing. We developed digital reverse transcription PCRs to monitor abundance of select mutations in Alpha and Delta VOCs in wastewater settled solids, applied these to July 2020-August 2021 samples from 2 large US metropolitan sewersheds, and compared results to estimates of VOC abundance from case isolate sequencing. Wastewater measurements tracked closely with case isolate estimates (Alpha, r

Indexed as

COVID-19SARS-CoV-2HumansRNA, ViralUnited StatesWastewaterWastewater-Based Epidemiological MonitoringRNA, ViralWastewatercoronavirus diseaseCOVID-19environmental monitoringpublic healthrespiratory infectionsSARS-CoV-2severe acute respiratory syndrome coronavirus 2United Statesvaccine-preventable diseasesviruseswastewaterzoonoses

Identifiers

PMID35349402
PMCPMC9045426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.