Evidence map›Paper›PMID 35349379›Full record

ArticleHuman vaccines & immunotherapeutics2022

Improving the availability of vaccines in primary healthcare facilities in South Africa: is the time right for a system redesign process?

Chinwe Juliana Iwu-Jaja, Portia Jordan, Ntombenhle Ngcobo, Anelisa Jaca, Chidozie Declan Iwu, Modest Mulenga, Charles Wiysonge

Open access · goldAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Chinwe Juliana Iwu-JajaDepartment of Nursing and Midwifery, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID 0000-0003-0765-7497
Portia JordanDepartment of Nursing and Midwifery, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID 0000-0003-4134-3221
Ntombenhle NgcoboIndependent Consultant, Pretoria, South Africa.ORCID 0000-0002-9666-6127
Anelisa JacaCochrane South Africa, South African Medical Research Council, Cape Town, South Africa.ORCID 0000-0002-9814-8374
Chidozie Declan IwuSchool of Health Systems and Public Health, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.ORCID 0000-0001-5721-6425
Modest MulengaDepartment of Public Health, Michael Chilifa Sata School of Medicine, Copperbelt University, Kitwe, Zambia.
Charles WiysongeCochrane South Africa, South African Medical Research Council, Cape Town, South Africa.ORCID 0000-0002-1273-4779
South African Medical Research Council · ZAStellenbosch University · ZACopperbelt University · ZMUniversity of Pretoria · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An uninterrupted supply of vaccines at different supply chain levels is a basic component of a functional immunization programme and care service. There can be no progress toward achieving universal health coverage and sustainable development without continuous availability of essential medicines and vaccines in healthcare facilities. Shortages of vaccines, particularly at health facility level is an issue of grave concern that requires urgent attention in South Africa. The causes of vaccine stock-outs are multifactorial and may be linked to a broader systems issue. These factors include challenges at higher levels such as delays in the delivery of stock from the pharmaceutical depot; health facility level factors, which include a lack of commitment from healthcare workers and managers; human resource factors, such as, staff shortages, and lack of skilled personnel. Therefore, there is a compelling need to address the factors associated with shortages of vaccines in health facilities. This paper highlights the challenges of vaccine availability in South Africa, the associated factors, the available interventions, and recommended interventions for the expanded programme on immunization in South Africa. We propose a system redesign approach as a potentially useful intervention.

Indexed as

Drugs, EssentialVaccinesHealth FacilitiesHumansPrimary Health CareSouth AfricaDrugs, EssentialVaccinesSouth Africastock-outsuniversal health coverageVaccine availability

Identifiers

PMID35349379
PMCPMC9009956
OpenAlexW4220795926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.